Mann RK - Search Results

1

Novel lipid modifications of secreted protein signals.

Mann RK, Beachy PA. Mann RK, et al. Annu Rev Biochem. 2004;73:891-923. doi: 10.1146/annurev.biochem.73.011303.073933. Annu Rev Biochem. 2004. PMID: 15189162 Review.

2

Genetic and biochemical definition of the Hedgehog receptor.

Zheng X, Mann RK, Sever N, Beachy PA. Zheng X, et al. Among authors: mann rk. Genes Dev. 2010 Jan 1;24(1):57-71. doi: 10.1101/gad.1870310. Genes Dev. 2010. PMID: 20048000 Free PMC article.

3

Hedgehog signal transduction via Smoothened association with a cytoplasmic complex scaffolded by the atypical kinesin, Costal-2.

Lum L, Zhang C, Oh S, Mann RK, von Kessler DP, Taipale J, Weis-Garcia F, Gong R, Wang B, Beachy PA. Lum L, et al. Among authors: mann rk. Mol Cell. 2003 Nov;12(5):1261-74. doi: 10.1016/s1097-2765(03)00426-x. Mol Cell. 2003. PMID: 14636583

4

Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine.

Taipale J, Chen JK, Cooper MK, Wang B, Mann RK, Milenkovic L, Scott MP, Beachy PA. Taipale J, et al. Among authors: mann rk. Nature. 2000 Aug 31;406(6799):1005-9. doi: 10.1038/35023008. Nature. 2000. PMID: 10984056

5

Cholesterol modification of proteins.

Mann RK, Beachy PA. Mann RK, et al. Biochim Biophys Acta. 2000 Dec 15;1529(1-3):188-202. doi: 10.1016/s1388-1981(00)00148-7. Biochim Biophys Acta. 2000. PMID: 11111088 Review.

6

Neuronal delivery of Hedgehog directs spatial patterning of taste organ regeneration.

Lu WJ, Mann RK, Nguyen A, Bi T, Silverstein M, Tang JY, Chen X, Beachy PA. Lu WJ, et al. Among authors: mann rk. Proc Natl Acad Sci U S A. 2018 Jan 9;115(2):E200-E209. doi: 10.1073/pnas.1719109115. Epub 2017 Dec 26. Proc Natl Acad Sci U S A. 2018. PMID: 29279401 Free PMC article.

7

Skinny hedgehog, an acyltransferase required for palmitoylation and activity of the hedgehog signal.

Chamoun Z, Mann RK, Nellen D, von Kessler DP, Bellotto M, Beachy PA, Basler K. Chamoun Z, et al. Among authors: mann rk. Science. 2001 Sep 14;293(5537):2080-4. doi: 10.1126/science.1064437. Epub 2001 Aug 2. Science. 2001. PMID: 11486055

8

Scube/You activity mediates release of dually lipid-modified Hedgehog signal in soluble form.

Creanga A, Glenn TD, Mann RK, Saunders AM, Talbot WS, Beachy PA. Creanga A, et al. Among authors: mann rk. Genes Dev. 2012 Jun 15;26(12):1312-25. doi: 10.1101/gad.191866.112. Epub 2012 Jun 7. Genes Dev. 2012. PMID: 22677548 Free PMC article.

9

Bifurcating action of Smoothened in Hedgehog signaling is mediated by Dlg5.

Chong YC, Mann RK, Zhao C, Kato M, Beachy PA. Chong YC, et al. Among authors: mann rk. Genes Dev. 2015 Feb 1;29(3):262-76. doi: 10.1101/gad.252676.114. Genes Dev. 2015. PMID: 25644602 Free PMC article.

10

Endogenous B-ring oxysterols inhibit the Hedgehog component Smoothened in a manner distinct from cyclopamine or side-chain oxysterols.

Sever N, Mann RK, Xu L, Snell WJ, Hernandez-Lara CI, Porter NA, Beachy PA. Sever N, et al. Among authors: mann rk. Proc Natl Acad Sci U S A. 2016 May 24;113(21):5904-9. doi: 10.1073/pnas.1604984113. Epub 2016 May 9. Proc Natl Acad Sci U S A. 2016. PMID: 27162362 Free PMC article.

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