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JAK-STAT blockade inhibits tumor initiation and clonogenic recovery of prostate cancer stem-like cells.
Kroon P, Berry PA, Stower MJ, Rodrigues G, Mann VM, Simms M, Bhasin D, Chettiar S, Li C, Li PK, Maitland NJ, Collins AT. Kroon P, et al. Cancer Res. 2013 Aug 15;73(16):5288-98. doi: 10.1158/0008-5472.CAN-13-0874. Epub 2013 Jul 3. Cancer Res. 2013. PMID: 23824741
Inhibition of the glucocorticoid receptor results in an enhanced miR-99a/100-mediated radiation response in stem-like cells from human prostate cancers.
Rane JK, Erb HH, Nappo G, Mann VM, Simms MS, Collins AT, Visakorpi T, Maitland NJ. Rane JK, et al. Oncotarget. 2016 Aug 9;7(32):51965-51980. doi: 10.18632/oncotarget.10207. Oncotarget. 2016. PMID: 27340920 Free PMC article.
Mechanisms of growth inhibition of primary prostate epithelial cells following gamma irradiation or photodynamic therapy include senescence, necrosis, and autophagy, but not apoptosis.
Frame FM, Savoie H, Bryden F, Giuntini F, Mann VM, Simms MS, Boyle RW, Maitland NJ. Frame FM, et al. Cancer Med. 2016 Jan;5(1):61-73. doi: 10.1002/cam4.553. Epub 2015 Nov 21. Cancer Med. 2016. PMID: 26590118 Free PMC article.
MicroRNA expression profile of primary prostate cancer stem cells as a source of biomarkers and therapeutic targets.
Rane JK, Scaravilli M, Ylipää A, Pellacani D, Mann VM, Simms MS, Nykter M, Collins AT, Visakorpi T, Maitland NJ. Rane JK, et al. Eur Urol. 2015 Jan;67(1):7-10. doi: 10.1016/j.eururo.2014.09.005. Epub 2014 Sep 16. Eur Urol. 2015. PMID: 25234358
Differential cytotoxic activity of a novel palladium-based compound on prostate cell lines, primary prostate epithelial cells and prostate stem cells.
Ulukaya E, Frame FM, Cevatemre B, Pellacani D, Walker H, Mann VM, Simms MS, Stower MJ, Yilmaz VT, Maitland NJ. Ulukaya E, et al. PLoS One. 2013 May 10;8(5):e64278. doi: 10.1371/journal.pone.0064278. Print 2013. PLoS One. 2013. PMID: 23675532 Free PMC article.
Monoallelic expression of TMPRSS2/ERG in prostate cancer stem cells.
Polson ES, Lewis JL, Celik H, Mann VM, Stower MJ, Simms MS, Rodrigues G, Collins AT, Maitland NJ. Polson ES, et al. Nat Commun. 2013;4:1623. doi: 10.1038/ncomms2627. Nat Commun. 2013. PMID: 23535644
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