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348 results
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Evolution of protein kinase signaling from yeast to man.
Manning G, Plowman GD, Hunter T, Sudarsanam S. Manning G, et al. Trends Biochem Sci. 2002 Oct;27(10):514-20. doi: 10.1016/s0968-0004(02)02179-5. Trends Biochem Sci. 2002. PMID: 12368087 Review.
The protein kinase complement of the human genome.
Manning G, Whyte DB, Martinez R, Hunter T, Sudarsanam S. Manning G, et al. Science. 2002 Dec 6;298(5600):1912-34. doi: 10.1126/science.1075762. Science. 2002. PMID: 12471243 Review.
Structural and functional diversity of the microbial kinome.
Kannan N, Taylor SS, Zhai Y, Venter JC, Manning G. Kannan N, et al. PLoS Biol. 2007 Mar;5(3):e17. doi: 10.1371/journal.pbio.0050017. PLoS Biol. 2007. PMID: 17355172 Free PMC article.
The dictyostelium kinome--analysis of the protein kinases from a simple model organism.
Goldberg JM, Manning G, Liu A, Fey P, Pilcher KE, Xu Y, Smith JL. Goldberg JM, et al. PLoS Genet. 2006 Mar;2(3):e38. doi: 10.1371/journal.pgen.0020038. Epub 2006 Mar 31. PLoS Genet. 2006. PMID: 16596165 Free PMC article.
Genomic overview of protein kinases.
Manning G. Manning G. WormBook. 2005 Dec 13:1-19. doi: 10.1895/wormbook.1.60.1. WormBook. 2005. PMID: 18050405 Free PMC article. Review.
The mouse kinome: discovery and comparative genomics of all mouse protein kinases.
Caenepeel S, Charydczak G, Sudarsanam S, Hunter T, Manning G. Caenepeel S, et al. Proc Natl Acad Sci U S A. 2004 Aug 10;101(32):11707-12. doi: 10.1073/pnas.0306880101. Epub 2004 Aug 2. Proc Natl Acad Sci U S A. 2004. PMID: 15289607 Free PMC article.
The STE20 kinase HGK is broadly expressed in human tumor cells and can modulate cellular transformation, invasion, and adhesion.
Wright JH, Wang X, Manning G, LaMere BJ, Le P, Zhu S, Khatry D, Flanagan PM, Buckley SD, Whyte DB, Howlett AR, Bischoff JR, Lipson KE, Jallal B. Wright JH, et al. Mol Cell Biol. 2003 Mar;23(6):2068-82. doi: 10.1128/mcb.23.6.2068-2082.2003. Mol Cell Biol. 2003. PMID: 12612079 Free PMC article.
A robust methodology to subclassify pseudokinases based on their nucleotide-binding properties.
Murphy JM, Zhang Q, Young SN, Reese ML, Bailey FP, Eyers PA, Ungureanu D, Hammaren H, Silvennoinen O, Varghese LN, Chen K, Tripaydonis A, Jura N, Fukuda K, Qin J, Nimchuk Z, Mudgett MB, Elowe S, Gee CL, Liu L, Daly RJ, Manning G, Babon JJ, Lucet IS. Murphy JM, et al. Biochem J. 2014 Jan 15;457(2):323-34. doi: 10.1042/BJ20131174. Biochem J. 2014. PMID: 24107129 Free PMC article.
Genomics and evolution of protein phosphatases.
Chen MJ, Dixon JE, Manning G. Chen MJ, et al. Sci Signal. 2017 Apr 11;10(474):eaag1796. doi: 10.1126/scisignal.aag1796. Sci Signal. 2017. PMID: 28400531
Necroptosis and Inflammation.
Newton K, Manning G. Newton K, et al. Annu Rev Biochem. 2016 Jun 2;85:743-63. doi: 10.1146/annurev-biochem-060815-014830. Epub 2016 Feb 8. Annu Rev Biochem. 2016. PMID: 26865533 Review.
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