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NuRD suppresses pluripotency gene expression to promote transcriptional heterogeneity and lineage commitment.
Reynolds N, Latos P, Hynes-Allen A, Loos R, Leaford D, O'Shaughnessy A, Mosaku O, Signolet J, Brennecke P, Kalkan T, Costello I, Humphreys P, Mansfield W, Nakagawa K, Strouboulis J, Behrens A, Bertone P, Hendrich B. Reynolds N, et al. Among authors: mansfield w. Cell Stem Cell. 2012 May 4;10(5):583-94. doi: 10.1016/j.stem.2012.02.020. Cell Stem Cell. 2012. PMID: 22560079 Free PMC article.
A practical and efficient cellular substrate for the generation of induced pluripotent stem cells from adults: blood-derived endothelial progenitor cells.
Geti I, Ormiston ML, Rouhani F, Toshner M, Movassagh M, Nichols J, Mansfield W, Southwood M, Bradley A, Rana AA, Vallier L, Morrell NW. Geti I, et al. Among authors: mansfield w. Stem Cells Transl Med. 2012 Dec;1(12):855-65. doi: 10.5966/sctm.2012-0093. Epub 2012 Nov 29. Stem Cells Transl Med. 2012. PMID: 23283547 Free PMC article.
Naive pluripotency is associated with global DNA hypomethylation.
Leitch HG, McEwen KR, Turp A, Encheva V, Carroll T, Grabole N, Mansfield W, Nashun B, Knezovich JG, Smith A, Surani MA, Hajkova P. Leitch HG, et al. Among authors: mansfield w. Nat Struct Mol Biol. 2013 Mar;20(3):311-6. doi: 10.1038/nsmb.2510. Epub 2013 Feb 17. Nat Struct Mol Biol. 2013. PMID: 23416945 Free PMC article.
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