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Mechanisms underlying differential responses to FGF signaling.
Dailey L, Ambrosetti D, Mansukhani A, Basilico C. Dailey L, et al. Among authors: mansukhani a. Cytokine Growth Factor Rev. 2005 Apr;16(2):233-47. doi: 10.1016/j.cytogfr.2005.01.007. Epub 2005 Mar 5. Cytokine Growth Factor Rev. 2005. PMID: 15863038 Review.
PPARγ agonists promote differentiation of cancer stem cells by restraining YAP transcriptional activity.
Basu-Roy U, Han E, Rattanakorn K, Gadi A, Verma N, Maurizi G, Gunaratne PH, Coarfa C, Kennedy OD, Garabedian MJ, Basilico C, Mansukhani A. Basu-Roy U, et al. Among authors: mansukhani a. Oncotarget. 2016 Sep 20;7(38):60954-60970. doi: 10.18632/oncotarget.11273. Oncotarget. 2016. PMID: 27528232 Free PMC article.
Sox2 antagonizes the Hippo pathway to maintain stemness in cancer cells.
Basu-Roy U, Bayin NS, Rattanakorn K, Han E, Placantonakis DG, Mansukhani A, Basilico C. Basu-Roy U, et al. Among authors: mansukhani a. Nat Commun. 2015 Apr 2;6:6411. doi: 10.1038/ncomms7411. Nat Commun. 2015. PMID: 25832504 Free PMC article.
Two FGF Receptor Kinase Molecules Act in Concert to Recruit and Transphosphorylate Phospholipase Cγ.
Huang Z, Marsiglia WM, Basu Roy U, Rahimi N, Ilghari D, Wang H, Chen H, Gai W, Blais S, Neubert TA, Mansukhani A, Traaseth NJ, Li X, Mohammadi M. Huang Z, et al. Among authors: mansukhani a. Mol Cell. 2016 Jan 7;61(1):98-110. doi: 10.1016/j.molcel.2015.11.010. Epub 2015 Dec 10. Mol Cell. 2016. PMID: 26687682 Free PMC article.
Perspectives on cancer stem cells in osteosarcoma.
Basu-Roy U, Basilico C, Mansukhani A. Basu-Roy U, et al. Among authors: mansukhani a. Cancer Lett. 2013 Sep 10;338(1):158-67. doi: 10.1016/j.canlet.2012.05.028. Epub 2012 May 29. Cancer Lett. 2013. PMID: 22659734 Free PMC article. Review.
Distinct functions of Sox2 control self-renewal and differentiation in the osteoblast lineage.
Seo E, Basu-Roy U, Zavadil J, Basilico C, Mansukhani A. Seo E, et al. Among authors: mansukhani a. Mol Cell Biol. 2011 Nov;31(22):4593-608. doi: 10.1128/MCB.05798-11. Epub 2011 Sep 19. Mol Cell Biol. 2011. PMID: 21930787 Free PMC article.
The transcription factor Sox2 is a key player in the maintenance of pluripotency and "stemness." We have previously shown that Sox2 maintains self-renewal in the osteoblast lineage while inhibiting differentiation (U. Basu-Roy et al., Cell Death Differ. 17:1345-1353, 2010; …
The transcription factor Sox2 is a key player in the maintenance of pluripotency and "stemness." We have previously shown that Sox2 m …
Early onset of craniosynostosis in an Apert mouse model reveals critical features of this pathology.
Holmes G, Rothschild G, Roy UB, Deng CX, Mansukhani A, Basilico C. Holmes G, et al. Among authors: mansukhani a. Dev Biol. 2009 Apr 15;328(2):273-84. doi: 10.1016/j.ydbio.2009.01.026. Epub 2009 Jan 29. Dev Biol. 2009. PMID: 19389359 Free PMC article.
Fibroblast growth factor signaling uses multiple mechanisms to inhibit Wnt-induced transcription in osteoblasts.
Ambrosetti D, Holmes G, Mansukhani A, Basilico C. Ambrosetti D, et al. Among authors: mansukhani a. Mol Cell Biol. 2008 Aug;28(15):4759-71. doi: 10.1128/MCB.01849-07. Epub 2008 May 27. Mol Cell Biol. 2008. PMID: 18505824 Free PMC article.
Osteoblast proliferation or differentiation is regulated by relative strengths of opposing signaling pathways.
Raucci A, Bellosta P, Grassi R, Basilico C, Mansukhani A. Raucci A, et al. Among authors: mansukhani a. J Cell Physiol. 2008 May;215(2):442-51. doi: 10.1002/jcp.21323. J Cell Physiol. 2008. PMID: 17960591
Sox2 induction by FGF and FGFR2 activating mutations inhibits Wnt signaling and osteoblast differentiation.
Mansukhani A, Ambrosetti D, Holmes G, Cornivelli L, Basilico C. Mansukhani A, et al. J Cell Biol. 2005 Mar 28;168(7):1065-76. doi: 10.1083/jcb.200409182. Epub 2005 Mar 21. J Cell Biol. 2005. PMID: 15781477 Free PMC article.
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