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Preictal dysfunctions of inhibitory interneurons paradoxically lead to their rebound hyperactivity and to low-voltage-fast onset seizures in Dravet syndrome.
Capitano F, Kuchenbuch M, Lavigne J, Chaptoukaev H, Zuluaga MA, Lorenzi M, Nabbout R, Mantegazza M. Capitano F, et al. Among authors: mantegazza m. Proc Natl Acad Sci U S A. 2024 Jun 4;121(23):e2316364121. doi: 10.1073/pnas.2316364121. Epub 2024 May 29. Proc Natl Acad Sci U S A. 2024. PMID: 38809712 Free PMC article.
Action potential initiation in neocortical inhibitory interneurons.
Li T, Tian C, Scalmani P, Frassoni C, Mantegazza M, Wang Y, Yang M, Wu S, Shu Y. Li T, et al. Among authors: mantegazza m. PLoS Biol. 2014 Sep 9;12(9):e1001944. doi: 10.1371/journal.pbio.1001944. eCollection 2014 Sep. PLoS Biol. 2014. PMID: 25203314 Free PMC article.
Impaired action potential initiation in GABAergic interneurons causes hyperexcitable networks in an epileptic mouse model carrying a human Na(V)1.1 mutation.
Hedrich UB, Liautard C, Kirschenbaum D, Pofahl M, Lavigne J, Liu Y, Theiss S, Slotta J, Escayg A, Dihné M, Beck H, Mantegazza M, Lerche H. Hedrich UB, et al. Among authors: mantegazza m. J Neurosci. 2014 Nov 5;34(45):14874-89. doi: 10.1523/JNEUROSCI.0721-14.2014. J Neurosci. 2014. PMID: 25378155 Free PMC article.
A two-hit story: Seizures and genetic mutation interaction sets phenotype severity in SCN1A epilepsies.
Salgueiro-Pereira AR, Duprat F, Pousinha PA, Loucif A, Douchamps V, Regondi C, Ayrault M, Eugie M, Stunault MI, Escayg A, Goutagny R, Gnatkovsky V, Frassoni C, Marie H, Bethus I, Mantegazza M. Salgueiro-Pereira AR, et al. Among authors: mantegazza m. Neurobiol Dis. 2019 May;125:31-44. doi: 10.1016/j.nbd.2019.01.006. Epub 2019 Jan 17. Neurobiol Dis. 2019. PMID: 30659983
96 results