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Structurally Novel Antiestrogens Elicit Differential Responses from Constitutively Active Mutant Estrogen Receptors in Breast Cancer Cells and Tumors.
Zhao Y, Laws MJ, Guillen VS, Ziegler Y, Min J, Sharma A, Kim SH, Chu D, Park BH, Oesterreich S, Mao C, Shapiro DJ, Nettles KW, Katzenellenbogen JA, Katzenellenbogen BS. Zhao Y, et al. Among authors: mao c. Cancer Res. 2017 Oct 15;77(20):5602-5613. doi: 10.1158/0008-5472.CAN-17-1265. Epub 2017 Sep 13. Cancer Res. 2017. PMID: 28904064 Free PMC article.
A noncompetitive small molecule inhibitor of estrogen-regulated gene expression and breast cancer cell growth that enhances proteasome-dependent degradation of estrogen receptor {alpha}.
Kretzer NM, Cherian MT, Mao C, Aninye IO, Reynolds PD, Schiff R, Hergenrother PJ, Nordeen SK, Wilson EM, Shapiro DJ. Kretzer NM, et al. Among authors: mao c. J Biol Chem. 2010 Dec 31;285(53):41863-73. doi: 10.1074/jbc.M110.183723. Epub 2010 Nov 1. J Biol Chem. 2010. PMID: 21041310 Free PMC article.
3,616 results