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159 results
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A rule for termination-codon position within intron-containing genes: when nonsense affects RNA abundance.
Nagy E, Maquat LE. Nagy E, et al. Among authors: maquat le. Trends Biochem Sci. 1998 Jun;23(6):198-9. doi: 10.1016/s0968-0004(98)01208-0. Trends Biochem Sci. 1998. PMID: 9644970 Review. No abstract available.
Applying nonsense-mediated mRNA decay research to the clinic: progress and challenges.
Kuzmiak HA, Maquat LE. Kuzmiak HA, et al. Among authors: maquat le. Trends Mol Med. 2006 Jul;12(7):306-16. doi: 10.1016/j.molmed.2006.05.005. Epub 2006 Jun 16. Trends Mol Med. 2006. PMID: 16782405 Review.
An enemy within: fly reconnaissance deploys an endonuclease to destroy nonsense-containing mRNA.
Valencia-Sánchez MA, Maquat LE. Valencia-Sánchez MA, et al. Among authors: maquat le. Trends Cell Biol. 2004 Nov;14(11):594-7. doi: 10.1016/j.tcb.2004.09.010. Trends Cell Biol. 2004. PMID: 15519847 Review.
Nonsense-mediated decay of mRNA for the selenoprotein phospholipid hydroperoxide glutathione peroxidase is detectable in cultured cells but masked or inhibited in rat tissues.
Sun X, Li X, Moriarty PM, Henics T, LaDuca JP, Maquat LE. Sun X, et al. Among authors: maquat le. Mol Biol Cell. 2001 Apr;12(4):1009-17. doi: 10.1091/mbc.12.4.1009. Mol Biol Cell. 2001. PMID: 11294903 Free PMC article.
Selenium deficiency reduces the abundance of mRNA for Se-dependent glutathione peroxidase 1 by a UGA-dependent mechanism likely to be nonsense codon-mediated decay of cytoplasmic mRNA.
Moriarty PM, Reddy CC, Maquat LE. Moriarty PM, et al. Among authors: maquat le. Mol Cell Biol. 1998 May;18(5):2932-9. doi: 10.1128/mcb.18.5.2932. Mol Cell Biol. 1998. PMID: 9566912 Free PMC article.
Pre-mRNA splicing alters mRNP composition: evidence for stable association of proteins at exon-exon junctions.
Le Hir H, Moore MJ, Maquat LE. Le Hir H, et al. Among authors: maquat le. Genes Dev. 2000 May 1;14(9):1098-108. Genes Dev. 2000. PMID: 10809668 Free PMC article.
Nonsense-mediated decay of glutathione peroxidase 1 mRNA in the cytoplasm depends on intron position.
Sun X, Moriarty PM, Maquat LE. Sun X, et al. Among authors: maquat le. EMBO J. 2000 Sep 1;19(17):4734-44. doi: 10.1093/emboj/19.17.4734. EMBO J. 2000. PMID: 10970865 Free PMC article.
At least one intron is required for the nonsense-mediated decay of triosephosphate isomerase mRNA: a possible link between nuclear splicing and cytoplasmic translation.
Zhang J, Sun X, Qian Y, LaDuca JP, Maquat LE. Zhang J, et al. Among authors: maquat le. Mol Cell Biol. 1998 Sep;18(9):5272-83. doi: 10.1128/mcb.18.9.5272. Mol Cell Biol. 1998. PMID: 9710612 Free PMC article.
A mutated human homologue to yeast Upf1 protein has a dominant-negative effect on the decay of nonsense-containing mRNAs in mammalian cells.
Sun X, Perlick HA, Dietz HC, Maquat LE. Sun X, et al. Among authors: maquat le. Proc Natl Acad Sci U S A. 1998 Aug 18;95(17):10009-14. doi: 10.1073/pnas.95.17.10009. Proc Natl Acad Sci U S A. 1998. PMID: 9707591 Free PMC article.
Intron function in the nonsense-mediated decay of beta-globin mRNA: indications that pre-mRNA splicing in the nucleus can influence mRNA translation in the cytoplasm.
Zhang J, Sun X, Qian Y, Maquat LE. Zhang J, et al. Among authors: maquat le. RNA. 1998 Jul;4(7):801-15. doi: 10.1017/s1355838298971849. RNA. 1998. PMID: 9671053 Free PMC article.
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