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Loss of Tribbles pseudokinase-3 promotes Akt-driven tumorigenesis via FOXO inactivation.
Salazar M, Lorente M, García-Taboada E, Pérez Gómez E, Dávila D, Zúñiga-García P, María Flores J, Rodríguez A, Hegedus Z, Mosén-Ansorena D, Aransay AM, Hernández-Tiedra S, López-Valero I, Quintanilla M, Sánchez C, Iovanna JL, Dusetti N, Guzmán M, Francis SE, Carracedo A, Kiss-Toth E, Velasco G. Salazar M, et al. Among authors: maria flores j. Cell Death Differ. 2015 Jan;22(1):131-44. doi: 10.1038/cdd.2014.133. Epub 2014 Aug 29. Cell Death Differ. 2015. PMID: 25168244 Free PMC article.
The mTOR pathway is necessary for survival of mice with short telomeres.
Ferrara-Romeo I, Martinez P, Saraswati S, Whittemore K, Graña-Castro O, Thelma Poluha L, Serrano R, Hernandez-Encinas E, Blanco-Aparicio C, Maria Flores J, Blasco MA. Ferrara-Romeo I, et al. Among authors: maria flores j. Nat Commun. 2020 Mar 3;11(1):1168. doi: 10.1038/s41467-020-14962-1. Nat Commun. 2020. PMID: 32127537 Free PMC article.