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Phosphodiesterase inhibitory properties of losartan. Design and synthesis of new lead compounds.

Segarra V, Crespo MI, Pujol F, Beleta J, Doménech T, Miralpeix M, Palacios JM, Castro A, Martinez A. Segarra V, et al. Among authors: palacios jm. Bioorg Med Chem Lett. 1998 Mar 3;8(5):505-10. doi: 10.1016/s0960-894x(98)00058-4. Bioorg Med Chem Lett. 1998. PMID: 9871607

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Functional and biochemical evidence for diazepam as a cyclic nucleotide phosphodiesterase type 4 inhibitor.

Collado MC, Beleta J, Martinez E, Miralpeix M, Domènech T, Palacios JM, Hernández J. Collado MC, et al. Among authors: palacios jm. Br J Pharmacol. 1998 Mar;123(6):1047-54. doi: 10.1038/sj.bjp.0701698. Br J Pharmacol. 1998. PMID: 9559885 Free PMC article.

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