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Depleting tumor-specific Tregs at a single site eradicates disseminated tumors.
Marabelle A, Kohrt H, Sagiv-Barfi I, Ajami B, Axtell RC, Zhou G, Rajapaksa R, Green MR, Torchia J, Brody J, Luong R, Rosenblum MD, Steinman L, Levitsky HI, Tse V, Levy R. Marabelle A, et al. J Clin Invest. 2013 Jun;123(6):2447-63. doi: 10.1172/JCI64859. J Clin Invest. 2013. PMID: 23728179 Free PMC article.
Combination strategies to enhance antitumor ADCC.
Kohrt HE, Houot R, Marabelle A, Cho HJ, Osman K, Goldstein M, Levy R, Brody J. Kohrt HE, et al. Among authors: marabelle a. Immunotherapy. 2012 May;4(5):511-27. doi: 10.2217/imt.12.38. Immunotherapy. 2012. PMID: 22642334 Free PMC article. Review.
Anti-KIR antibody enhancement of anti-lymphoma activity of natural killer cells as monotherapy and in combination with anti-CD20 antibodies.
Kohrt HE, Thielens A, Marabelle A, Sagiv-Barfi I, Sola C, Chanuc F, Fuseri N, Bonnafous C, Czerwinski D, Rajapaksa A, Waller E, Ugolini S, Vivier E, Romagné F, Levy R, Bléry M, André P. Kohrt HE, et al. Among authors: marabelle a. Blood. 2014 Jan 30;123(5):678-86. doi: 10.1182/blood-2013-08-519199. Epub 2013 Dec 10. Blood. 2014. PMID: 24326534 Free PMC article.
Targeting CD137 enhances the efficacy of cetuximab.
Kohrt HE, Colevas AD, Houot R, Weiskopf K, Goldstein MJ, Lund P, Mueller A, Sagiv-Barfi I, Marabelle A, Lira R, Troutner E, Richards L, Rajapaska A, Hebb J, Chester C, Waller E, Ostashko A, Weng WK, Chen L, Czerwinski D, Fu YX, Sunwoo J, Levy R. Kohrt HE, et al. Among authors: marabelle a. J Clin Invest. 2014 Jun;124(6):2668-82. doi: 10.1172/JCI73014. Epub 2014 May 16. J Clin Invest. 2014. PMID: 24837434 Free PMC article. Retracted.
Radiotherapy and toll-like receptor agonists.
Marabelle A, Filatenkov A, Sagiv-Barfi I, Kohrt H. Marabelle A, et al. Semin Radiat Oncol. 2015 Jan;25(1):34-9. doi: 10.1016/j.semradonc.2014.07.006. Semin Radiat Oncol. 2015. PMID: 25481264 Review.
268 results