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Human lung tissue explants reveal novel interactions during Legionella pneumophila infections.
Jäger J, Marwitz S, Tiefenau J, Rasch J, Shevchuk O, Kugler C, Goldmann T, Steinert M. Jäger J, et al. Among authors: rasch j. Infect Immun. 2014 Jan;82(1):275-85. doi: 10.1128/IAI.00703-13. Epub 2013 Oct 28. Infect Immun. 2014. PMID: 24166955 Free PMC article.
The transcriptional response included the upregulation of uteroglobin and the downregulation of the macrophage receptor with collagenous structure (MARCO). Immunohistochemistry confirmed the downregulation of MARCO at sites of pathogen-induced tissue destruction. .. …
The transcriptional response included the upregulation of uteroglobin and the downregulation of the macrophage receptor with collagenous str …