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207 results

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Page 1
Plasminogen activation triggers transthyretin amyloidogenesis in vitro.
Mangione PP, Verona G, Corazza A, Marcoux J, Canetti D, Giorgetti S, Raimondi S, Stoppini M, Esposito M, Relini A, Canale C, Valli M, Marchese L, Faravelli G, Obici L, Hawkins PN, Taylor GW, Gillmore JD, Pepys MB, Bellotti V. Mangione PP, et al. Among authors: marcoux j. J Biol Chem. 2018 Sep 14;293(37):14192-14199. doi: 10.1074/jbc.RA118.003990. Epub 2018 Jul 17. J Biol Chem. 2018. PMID: 30018138 Free PMC article.
Proteolytic cleavage of Ser52Pro variant transthyretin triggers its amyloid fibrillogenesis.
Mangione PP, Porcari R, Gillmore JD, Pucci P, Monti M, Porcari M, Giorgetti S, Marchese L, Raimondi S, Serpell LC, Chen W, Relini A, Marcoux J, Clatworthy IR, Taylor GW, Tennent GA, Robinson CV, Hawkins PN, Stoppini M, Wood SP, Pepys MB, Bellotti V. Mangione PP, et al. Among authors: marcoux j. Proc Natl Acad Sci U S A. 2014 Jan 28;111(4):1539-44. doi: 10.1073/pnas.1317488111. Epub 2014 Jan 13. Proc Natl Acad Sci U S A. 2014. PMID: 24474780 Free PMC article.
A novel mechano-enzymatic cleavage mechanism underlies transthyretin amyloidogenesis.
Marcoux J, Mangione PP, Porcari R, Degiacomi MT, Verona G, Taylor GW, Giorgetti S, Raimondi S, Sanglier-Cianférani S, Benesch JL, Cecconi C, Naqvi MM, Gillmore JD, Hawkins PN, Stoppini M, Robinson CV, Pepys MB, Bellotti V. Marcoux J, et al. EMBO Mol Med. 2015 Oct;7(10):1337-49. doi: 10.15252/emmm.201505357. EMBO Mol Med. 2015. PMID: 26286619 Free PMC article.
A specific nanobody prevents amyloidogenesis of D76N β2-microglobulin in vitro and modifies its tissue distribution in vivo.
Raimondi S, Porcari R, Mangione PP, Verona G, Marcoux J, Giorgetti S, Taylor GW, Ellmerich S, Ballico M, Zanini S, Pardon E, Al-Shawi R, Simons JP, Corazza A, Fogolari F, Leri M, Stefani M, Bucciantini M, Gillmore JD, Hawkins PN, Valli M, Stoppini M, Robinson CV, Steyaert J, Esposito G, Bellotti V. Raimondi S, et al. Among authors: marcoux j. Sci Rep. 2017 Apr 21;7:46711. doi: 10.1038/srep46711. Sci Rep. 2017. PMID: 28429761 Free PMC article.
The final assembly of trehalose polyphleates takes place within the outer layer of the mycobacterial cell envelope.
Thouvenel L, Prevot G, Chiaradia L, Parra J, Mouton-Barbosa E, Locard-Paulet M, Marcoux J, Tropis M, Burlet-Schiltz O, Daffé M, Guilhot C, Etienne G, Chalut C. Thouvenel L, et al. Among authors: marcoux j. J Biol Chem. 2020 Aug 7;295(32):11184-11194. doi: 10.1074/jbc.RA120.013299. Epub 2020 Jun 17. J Biol Chem. 2020. PMID: 32554804 Free PMC article.
Small molecule-based targeting of TTD-A dimerization to control TFIIH transcriptional activity represents a potential strategy for anticancer therapy.
Gervais V, Muller I, Mari PO, Mourcet A, Movellan KT, Ramos P, Marcoux J, Guillet V, Javaid S, Burlet-Schiltz O, Czaplicki G, Milon A, Giglia-Mari G. Gervais V, et al. Among authors: marcoux j. J Biol Chem. 2018 Sep 28;293(39):14974-14988. doi: 10.1074/jbc.RA118.003444. Epub 2018 Aug 1. J Biol Chem. 2018. PMID: 30068551 Free PMC article.
Proteasome complexes experience profound structural and functional rearrangements throughout mammalian spermatogenesis.
Živković D, Sanchez Dafun A, Menneteau T, Schahl A, Lise S, Kervarrec C, Toste Rêgo A, da Fonseca PCA, Chavent M, Pineau C, Burlet-Schiltz O, Marcoux J, Bousquet MP. Živković D, et al. Among authors: marcoux j. Proc Natl Acad Sci U S A. 2022 Apr 12;119(15):e2116826119. doi: 10.1073/pnas.2116826119. Epub 2022 Apr 4. Proc Natl Acad Sci U S A. 2022. PMID: 35377789 Free PMC article.
Steroid-based facial amphiphiles for stabilization and crystallization of membrane proteins.
Lee SC, Bennett BC, Hong WX, Fu Y, Baker KA, Marcoux J, Robinson CV, Ward AB, Halpert JR, Stevens RC, Stout CD, Yeager MJ, Zhang Q. Lee SC, et al. Among authors: marcoux j. Proc Natl Acad Sci U S A. 2013 Mar 26;110(13):E1203-11. doi: 10.1073/pnas.1221442110. Epub 2013 Mar 11. Proc Natl Acad Sci U S A. 2013. PMID: 23479627 Free PMC article.
207 results