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Local hyperthermia combined with radiotherapy and-/or chemotherapy: recent advances and promises for the future.
Datta NR, Ordóñez SG, Gaipl US, Paulides MM, Crezee H, Gellermann J, Marder D, Puric E, Bodis S. Datta NR, et al. Among authors: marder d. Cancer Treat Rev. 2015 Nov;41(9):742-53. doi: 10.1016/j.ctrv.2015.05.009. Epub 2015 May 27. Cancer Treat Rev. 2015. PMID: 26051911 Review.
Hyperthermia, one of the oldest forms of cancer treatment involves selective heating of tumor tissues to temperatures ranging between 39 and 45C. ...The review summarizes the outcomes from various clinical studies (both randomized and nonrandomized) where hyperthermia …
Hyperthermia, one of the oldest forms of cancer treatment involves selective heating of tumor tissues to temperatures ranging between …
Quality assurance guidelines for interstitial hyperthermia.
Dobšíček Trefná H, Schmidt M, van Rhoon GC, Kok HP, Gordeyev SS, Lamprecht U, Marder D, Nadobny J, Ghadjar P, Abdel-Rahman S, Kukiełka AM, Strnad V, Hurwitz MD, Vujaskovic Z, Diederich CJ, Stauffer PR, Crezee J. Dobšíček Trefná H, et al. Among authors: marder d. Int J Hyperthermia. 2019;36(1):277-294. doi: 10.1080/02656736.2018.1564155. Epub 2019 Jan 24. Int J Hyperthermia. 2019. PMID: 30676101 Free article.
Interstitial hyperthermia aims at tumor temperatures in the 40-44 C range as an adjunct to radiation or chemotherapy. ...Detailed instructions are provided on characterization and documentation of the performance of interstitial hyperthermia applicators to achieve r …
Interstitial hyperthermia aims at tumor temperatures in the 40-44 C range as an adjunct to radiation or chemotherapy. ...Detailed ins …
Quality assurance guidelines for superficial hyperthermia clinical trials : II. Technical requirements for heating devices.
Dobšíček Trefná H, Crezee J, Schmidt M, Marder D, Lamprecht U, Ehmann M, Nadobny J, Hartmann J, Lomax N, Abdel-Rahman S, Curto S, Bakker A, Hurwitz MD, Diederich CJ, Stauffer PR, Van Rhoon GC. Dobšíček Trefná H, et al. Among authors: marder d. Strahlenther Onkol. 2017 May;193(5):351-366. doi: 10.1007/s00066-017-1106-0. Epub 2017 Mar 1. Strahlenther Onkol. 2017. PMID: 28251250 Free PMC article. Review.
Quality assurance (QA) guidelines are essential to provide uniform execution of clinical trials with uniform quality hyperthermia treatments. This document outlines the requirements for appropriate QA of all current superficial heating equipment including electromagnetic ( …
Quality assurance (QA) guidelines are essential to provide uniform execution of clinical trials with uniform quality hyperthermia tre …
The addition of deep hyperthermia to gemcitabine-based chemoradiation may achieve enhanced survival in unresectable locally advanced adenocarcinoma of the pancreas.
Rogers SJ, Datta NR, Puric E, Timm O, Marder D, Khan S, Mamot C, Knuchel J, Siebenhüner A, Pestalozzi B, Guckenberger M, Bodis S, Riesterer O. Rogers SJ, et al. Among authors: marder d. Clin Transl Radiat Oncol. 2021 Jan 25;27:109-113. doi: 10.1016/j.ctro.2021.01.008. eCollection 2021 Mar. Clin Transl Radiat Oncol. 2021. PMID: 33598571 Free PMC article.
METHODS: Nine patients with LAPC were treated according to the HEATPAC Phase II trial protocol which consists of 4 cycles of FOLFORINOX chemotherapy followed by gemcitabine-based chemoradiation to 56 Gy combined with weekly deep hyperthermia and then a further 8 cycles of …
METHODS: Nine patients with LAPC were treated according to the HEATPAC Phase II trial protocol which consists of 4 cycles of FOLFORINOX chem …
Quantification of thermal dose in moderate clinical hyperthermia with radiotherapy: a relook using temperature-time area under the curve (AUC).
Datta NR, Marder D, Datta S, Meister A, Puric E, Stutz E, Rogers S, Eberle B, Timm O, Staruch M, Riesterer O, Bodis S. Datta NR, et al. Among authors: marder d. Int J Hyperthermia. 2021;38(1):296-307. doi: 10.1080/02656736.2021.1875060. Int J Hyperthermia. 2021. PMID: 33627018 Free article.
An alternative method centered on the actual time-temperature plot during each hyperthermia session and its prognostic feasibility is explored. METHODS AND MATERIALS: Patients with bladder cancer treated with weekly deep hyperthermia followed by radiotherapy were ev …
An alternative method centered on the actual time-temperature plot during each hyperthermia session and its prognostic feasibility is …
Quality assurance guidelines for superficial hyperthermia clinical trials: I. Clinical requirements.
Trefná HD, Crezee H, Schmidt M, Marder D, Lamprecht U, Ehmann M, Hartmann J, Nadobny J, Gellermann J, van Holthe N, Ghadjar P, Lomax N, Abdel-Rahman S, Bert C, Bakker A, Hurwitz MD, Diederich CJ, Stauffer PR, van Rhoon GC. Trefná HD, et al. Among authors: marder d. Int J Hyperthermia. 2017 Jun;33(4):471-482. doi: 10.1080/02656736.2016.1277791. Epub 2017 Jan 31. Int J Hyperthermia. 2017. PMID: 28049386 Free article.
Quality assurance guidelines are essential to provide uniform execution of clinical trials and treatment in the application of hyperthermia. This document provides definitions for a good hyperthermia treatment and identifies the clinical conditions where a certain …
Quality assurance guidelines are essential to provide uniform execution of clinical trials and treatment in the application of hypertherm …
Proton Irradiation with Hyperthermia in Unresectable Soft Tissue Sarcoma.
Datta NR, Schneider R, Puric E, Ahlhelm FJ, Marder D, Bodis S, Weber DC. Datta NR, et al. Among authors: marder d. Int J Part Ther. 2016 Fall;3(2):327-336. doi: 10.14338/IJPT-16-00016.1. Epub 2016 Dec 30. Int J Part Ther. 2016. PMID: 31772984 Free PMC article.
Both patients had declined the above-knee amputation that had been advised due to their involvement of the neurovascular bundles. They were, therefore recruited to the Hyperthermia and Proton Therapy in Unresectable Soft Tissue Sarcoma (HYPROSAR) study protocol (ClinicalTr …
Both patients had declined the above-knee amputation that had been advised due to their involvement of the neurovascular bundles. They were, …
Hyperthermia and reirradiation for locoregional recurrences in preirradiated breast cancers: a single institutional experience.
Datta NR, Puric E, Heüberger J, Marder D, Lomax N, Timm O, Memminger P, Bodis S. Datta NR, et al. Among authors: marder d. Swiss Med Wkly. 2015 Apr 23;145:w14133. doi: 10.4414/smw.2015.14133. eCollection 2015. Swiss Med Wkly. 2015. PMID: 25906357 Free article.
QUESTIONS UNDER STUDY: The aim of this retrospective analysis was to evaluate the safety and efficacy of local hyperthermia (HT) and reirradiation (ReRT) in the management of preirradiated locoregional recurrent breast cancers at Kantonsspital Aarau, Switzerland. ...All pa …
QUESTIONS UNDER STUDY: The aim of this retrospective analysis was to evaluate the safety and efficacy of local hyperthermia (HT) and …
A Pilot Study of Radiotherapy and Local Hyperthermia in Elderly Patients With Muscle-Invasive Bladder Cancers Unfit for Definitive Surgery or Chemoradiotherapy.
Datta NR, Stutz E, Puric E, Eberle B, Meister A, Marder D, Timm O, Rogers S, Wyler S, Bodis S. Datta NR, et al. Among authors: marder d. Front Oncol. 2019 Sep 10;9:889. doi: 10.3389/fonc.2019.00889. eCollection 2019. Front Oncol. 2019. PMID: 31552192 Free PMC article.
Purpose: To present the outcomes of a pilot study with hyperthermia (HT) and radiotherapy (RT) in elderly patients of muscle-invasive bladder cancers (MIBC) unfit for surgery or chemoradiotherapy (CTRT). ...
Purpose: To present the outcomes of a pilot study with hyperthermia (HT) and radiotherapy (RT) in elderly patients of muscle-invasive …
Early results and volumetric analysis after spot-scanning proton therapy with concomitant hyperthermia in large inoperable sacral chordomas.
Tran S, Puric E, Walser M, Poel R, Datta NR, Heuberger J, Pica A, Marder D, Lomax N, Bolsi A, Morach P, Bachtiary B, Seddon BM, Schneider R, Bodis S, Weber DC. Tran S, et al. Among authors: marder d. Br J Radiol. 2020 Mar;93(1107):20180883. doi: 10.1259/bjr.20180883. Epub 2019 May 14. Br J Radiol. 2020. PMID: 30943055 Free PMC article.
The aim of this study is assessing feasibility and reporting early results of patients treated with PT and concomitant hyperthermia (HT). METHODS: Patients had histologically proven unresectable sacral chordomas and received 70 Gy (relative biological effectiveness) in 2.5 …
The aim of this study is assessing feasibility and reporting early results of patients treated with PT and concomitant hyperthermia ( …
12 results