Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

My NCBI Filters
Text availability
Article attribute
Article type
Publication date

Search Results

108 results
Filters applied: . Clear all Results are displayed in a computed author sort order. Results by year timeline is unavailable
Page 1
Modelling the effect of SPION size in a stent assisted magnetic drug targeting system with interparticle interactions.
Mardinoglu A, Cregg PJ. Mardinoglu A, et al. ScientificWorldJournal. 2015;2015:618658. doi: 10.1155/2015/618658. Epub 2015 Mar 1. ScientificWorldJournal. 2015. PMID: 25815370 Free PMC article.
Cancer is a leading cause of death worldwide and it is caused by the interaction of genomic, environmental, and lifestyle factors. ...Here, we develop a mathematical model for studying the interactions between the MDCPs enriched with three different diameters of SPI …
Cancer is a leading cause of death worldwide and it is caused by the interaction of genomic, environmental, and lifestyle factors. .. …
A genome-wide transcriptomic analysis of protein-coding genes in human blood cells.
Uhlen M, Karlsson MJ, Zhong W, Tebani A, Pou C, Mikes J, Lakshmikanth T, Forsström B, Edfors F, Odeberg J, Mardinoglu A, Zhang C, von Feilitzen K, Mulder J, Sjöstedt E, Hober A, Oksvold P, Zwahlen M, Ponten F, Lindskog C, Sivertsson Å, Fagerberg L, Brodin P. Uhlen M, et al. Science. 2019 Dec 20;366(6472):eaax9198. doi: 10.1126/science.aax9198. Science. 2019. PMID: 31857451
In this study, we performed a genome-wide transcriptomic analysis of protein-coding genes in sorted blood immune cell populations to characterize the expression levels of each individual gene across the blood cell types. ...This allows for a genome-wide exploration …
In this study, we performed a genome-wide transcriptomic analysis of protein-coding genes in sorted blood immune cell populations to …
An atlas of the protein-coding genes in the human, pig, and mouse brain.
Sjöstedt E, Zhong W, Fagerberg L, Karlsson M, Mitsios N, Adori C, Oksvold P, Edfors F, Limiszewska A, Hikmet F, Huang J, Du Y, Lin L, Dong Z, Yang L, Liu X, Jiang H, Xu X, Wang J, Yang H, Bolund L, Mardinoglu A, Zhang C, von Feilitzen K, Lindskog C, Pontén F, Luo Y, Hökfelt T, Uhlén M, Mulder J. Sjöstedt E, et al. Science. 2020 Mar 6;367(6482):eaay5947. doi: 10.1126/science.aay5947. Science. 2020. PMID: 32139519
To expand our basic understanding of the neurobiology of the brain and its diseases, we performed a comprehensive molecular dissection of 10 major brain regions and multiple subregions using a variety of transcriptomics methods and antibody-based mapping. ...
To expand our basic understanding of the neurobiology of the brain and its diseases, we performed a comprehensive molecular dissectio …
Novel anti-Alzheimer phenol-lipoyl hybrids: Synthesis, physico-chemical characterization, and biological evaluation.
Pagoni A, Marinelli L, Di Stefano A, Ciulla M, Turkez H, Mardinoglu A, Vassiliou S, Cacciatore I. Pagoni A, et al. Eur J Med Chem. 2020 Jan 15;186:111880. doi: 10.1016/j.ejmech.2019.111880. Epub 2019 Nov 12. Eur J Med Chem. 2020. PMID: 31753513
To date, drugs that hit a single target are inadequate for the treatment of neurodegenerative diseases, such as Alzheimer's or Parkinson's diseases. The development of multitarget ligands, able to interact with the different pathways involved in the progession of these dis …
To date, drugs that hit a single target are inadequate for the treatment of neurodegenerative diseases, such as Alzheimer's or Parkin …
An adipocyte-specific defect in oxidative phosphorylation increases systemic energy expenditure and protects against diet-induced obesity in mouse models.
Choi MJ, Jung SB, Lee SE, Kang SG, Lee JH, Ryu MJ, Chung HK, Chang JY, Kim YK, Hong HJ, Kim H, Kim HJ, Lee CH, Mardinoglu A, Yi HS, Shong M. Choi MJ, et al. Diabetologia. 2020 Apr;63(4):837-852. doi: 10.1007/s00125-019-05082-7. Epub 2020 Jan 10. Diabetologia. 2020. PMID: 31925461
AdKO mice fed a normal chow or high-fat diet were evaluated for glucose homeostasis, weight gain and energy expenditure (EE). ...
AdKO mice fed a normal chow or high-fat diet were evaluated for glucose homeostasis, weight gain and energy expenditure (EE). ...
Genome-Scale Metabolic Modeling of Glioblastoma Reveals Promising Targets for Drug Development.
Larsson I, Uhlén M, Zhang C, Mardinoglu A. Larsson I, et al. Among authors: mardinoglu a. Front Genet. 2020 Apr 17;11:381. doi: 10.3389/fgene.2020.00381. eCollection 2020. Front Genet. 2020. PMID: 32362913 Free PMC article.
Boosting Natural Killer Cell-Mediated Targeting of Sarcoma Through DNAM-1 and NKG2D.
Sayitoglu EC, Georgoudaki AM, Chrobok M, Ozkazanc D, Josey BJ, Arif M, Kusser K, Hartman M, Chinn TM, Potens R, Pamukcu C, Krueger R, Zhang C, Mardinoglu A, Alici E, Temple HT, Sutlu T, Duru AD. Sayitoglu EC, et al. Front Immunol. 2020 Jan 28;11:40. doi: 10.3389/fimmu.2020.00040. eCollection 2020. Front Immunol. 2020. PMID: 32082316 Free PMC article.
We also applied a functional screening approach to identify relevant NK cell receptor/ligand interactions that induce efficient anti-tumor responses using a panel NK-92 cell lines GM to over-express 12 different activating receptors. ...In conclusion, DNAM-1 or NKG2 …
We also applied a functional screening approach to identify relevant NK cell receptor/ligand interactions that induce efficient anti- …
Systems medicine and metabolic modelling.
Mardinoglu A, Nielsen J. Mardinoglu A, et al. J Intern Med. 2012 Feb;271(2):142-54. doi: 10.1111/j.1365-2796.2011.02493.x. J Intern Med. 2012. PMID: 22142312 Review.
Genome-scale modeling of human metabolism - a systems biology approach.
Mardinoglu A, Gatto F, Nielsen J. Mardinoglu A, et al. Biotechnol J. 2013 Sep;8(9):985-96. doi: 10.1002/biot.201200275. Epub 2013 Apr 24. Biotechnol J. 2013. PMID: 23613448 Review.
Genome-scale metabolic models (GEMs) have been employed for studying human metabolism in a systematic manner, as well as for understanding complex human diseases. ...Finally, recent advancements in genome-scale modeling and the future challenge of developing a model …
Genome-scale metabolic models (GEMs) have been employed for studying human metabolism in a systematic manner, as well as for understa …
Identification of anticancer drugs for hepatocellular carcinoma through personalized genome-scale metabolic modeling.
Agren R, Mardinoglu A, Asplund A, Kampf C, Uhlen M, Nielsen J. Agren R, et al. Mol Syst Biol. 2014 Mar 19;10(3):721. doi: 10.1002/msb.145122. Mol Syst Biol. 2014. PMID: 24646661 Free PMC article.
Genome-scale metabolic models (GEMs) have proven useful as scaffolds for the integration of omics data for understanding the genotype-phenotype relationship in a mechanistic manner. ...We used this information to reconstruct personalized GEMs for six HCC patients based on …
Genome-scale metabolic models (GEMs) have proven useful as scaffolds for the integration of omics data for understanding the genotype-phenot …
108 results
Jump to page
Feedback