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The glucose transporter 2 regulates CD8+ T cell function via environment sensing.
Fu H, Vuononvirta J, Fanti S, Bonacina F, D'Amati A, Wang G, Poobalasingam T, Fankhaenel M, Lucchesi D, Coleby R, Tarussio D, Thorens B, Hearnden RJ, Longhi MP, Grevitt P, Sheikh MH, Solito E, Godinho SA, Bombardieri M, Smith DM, Cooper D, Iqbal AJ, Rathmell JC, Schaefer S, Morales V, Bianchi K, Norata GD, Marelli-Berg FM. Fu H, et al. Among authors: marelli berg fm. Nat Metab. 2023 Nov;5(11):1969-1985. doi: 10.1038/s42255-023-00913-9. Epub 2023 Oct 26. Nat Metab. 2023. PMID: 37884694 Free PMC article.
Obesity-Induced Metabolic Stress Leads to Biased Effector Memory CD4+ T Cell Differentiation via PI3K p110δ-Akt-Mediated Signals.
Mauro C, Smith J, Cucchi D, Coe D, Fu H, Bonacina F, Baragetti A, Cermenati G, Caruso D, Mitro N, Catapano AL, Ammirati E, Longhi MP, Okkenhaug K, Norata GD, Marelli-Berg FM. Mauro C, et al. Cell Metab. 2017 Mar 7;25(3):593-609. doi: 10.1016/j.cmet.2017.01.008. Epub 2017 Feb 9. Cell Metab. 2017. PMID: 28190771 Free PMC article.
Preservation of microvascular barrier function requires CD31 receptor-induced metabolic reprogramming.
Cheung KCP, Fanti S, Mauro C, Wang G, Nair AS, Fu H, Angeletti S, Spoto S, Fogolari M, Romano F, Aksentijevic D, Liu W, Li B, Cheng L, Jiang L, Vuononvirta J, Poobalasingam TR, Smith DM, Ciccozzi M, Solito E, Marelli-Berg FM. Cheung KCP, et al. Among authors: marelli berg fm. Nat Commun. 2020 Jul 17;11(1):3595. doi: 10.1038/s41467-020-17329-8. Nat Commun. 2020. PMID: 32681081 Free PMC article.
Metabolic regulation of T lymphocyte motility and migration.
Vuononvirta J, Marelli-Berg FM, Poobalasingam T. Vuononvirta J, et al. Among authors: marelli berg fm. Mol Aspects Med. 2021 Feb;77:100888. doi: 10.1016/j.mam.2020.100888. Epub 2020 Aug 16. Mol Aspects Med. 2021. PMID: 32814624 Review.
Loss of voltage-gated hydrogen channel 1 expression reveals heterogeneous metabolic adaptation to intracellular acidification by T cells.
Coe D, Poobalasingam T, Fu H, Bonacina F, Wang G, Morales V, Moregola A, Mitro N, Cheung KC, Ward EJ, Nadkarni S, Aksentijevic D, Bianchi K, Norata GD, Capasso M, Marelli-Berg FM. Coe D, et al. Among authors: marelli berg fm. JCI Insight. 2022 May 23;7(10):e147814. doi: 10.1172/jci.insight.147814. JCI Insight. 2022. PMID: 35472029 Free PMC article.
Mechanisms of T cell organotropism.
Fu H, Ward EJ, Marelli-Berg FM. Fu H, et al. Cell Mol Life Sci. 2016 Aug;73(16):3009-33. doi: 10.1007/s00018-016-2211-4. Epub 2016 Apr 1. Cell Mol Life Sci. 2016. PMID: 27038487 Free PMC article. Review.
The low-density lipoprotein receptor-mTORC1 axis coordinates CD8+ T cell activation.
Bonacina F, Moregola A, Svecla M, Coe D, Uboldi P, Fraire S, Beretta S, Beretta G, Pellegatta F, Catapano AL, Marelli-Berg FM, Norata GD. Bonacina F, et al. Among authors: marelli berg fm. J Cell Biol. 2022 Nov 7;221(11):e202202011. doi: 10.1083/jcb.202202011. Epub 2022 Sep 21. J Cell Biol. 2022. PMID: 36129440 Free PMC article.
Regulatory T Cell Migration Is Dependent on Glucokinase-Mediated Glycolysis.
Kishore M, Cheung KCP, Fu H, Bonacina F, Wang G, Coe D, Ward EJ, Colamatteo A, Jangani M, Baragetti A, Matarese G, Smith DM, Haas R, Mauro C, Wraith DC, Okkenhaug K, Catapano AL, De Rosa V, Norata GD, Marelli-Berg FM. Kishore M, et al. Immunity. 2017 Nov 21;47(5):875-889.e10. doi: 10.1016/j.immuni.2017.10.017. Immunity. 2017. PMID: 29166588 Free PMC article.
103 results