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The Polycomb complex PRC2 and its mark in life.
Margueron R, Reinberg D. Margueron R, et al. Nature. 2011 Jan 20;469(7330):343-9. doi: 10.1038/nature09784. Nature. 2011. PMID: 21248841 Free PMC article. Review.
Jarid2 Methylation via the PRC2 Complex Regulates H3K27me3 Deposition during Cell Differentiation.
Sanulli S, Justin N, Teissandier A, Ancelin K, Portoso M, Caron M, Michaud A, Lombard B, da Rocha ST, Offer J, Loew D, Servant N, Wassef M, Burlina F, Gamblin SJ, Heard E, Margueron R. Sanulli S, et al. Among authors: margueron r. Mol Cell. 2015 Mar 5;57(5):769-783. doi: 10.1016/j.molcel.2014.12.020. Epub 2015 Jan 22. Mol Cell. 2015. PMID: 25620564 Free PMC article.
Imprinting control regions (ICRs) are marked by mono-allelic bivalent chromatin when transcriptionally inactive.
Maupetit-Méhouas S, Montibus B, Nury D, Tayama C, Wassef M, Kota SK, Fogli A, Cerqueira Campos F, Hata K, Feil R, Margueron R, Nakabayashi K, Court F, Arnaud P. Maupetit-Méhouas S, et al. Among authors: margueron r. Nucleic Acids Res. 2016 Jan 29;44(2):621-35. doi: 10.1093/nar/gkv960. Epub 2015 Sep 22. Nucleic Acids Res. 2016. PMID: 26400168 Free PMC article.
Impaired PRC2 activity promotes transcriptional instability and favors breast tumorigenesis.
Wassef M, Rodilla V, Teissandier A, Zeitouni B, Gruel N, Sadacca B, Irondelle M, Charruel M, Ducos B, Michaud A, Caron M, Marangoni E, Chavrier P, Le Tourneau C, Kamal M, Pasmant E, Vidaud M, Servant N, Reyal F, Meseure D, Vincent-Salomon A, Fre S, Margueron R. Wassef M, et al. Among authors: margueron r. Genes Dev. 2015 Dec 15;29(24):2547-62. doi: 10.1101/gad.269522.115. Epub 2015 Dec 4. Genes Dev. 2015. PMID: 26637281 Free PMC article.
The Multiple Facets of PRC2 Alterations in Cancers.
Wassef M, Margueron R. Wassef M, et al. Among authors: margueron r. J Mol Biol. 2017 Jun 30;429(13):1978-1993. doi: 10.1016/j.jmb.2016.10.012. Epub 2016 Oct 12. J Mol Biol. 2017. PMID: 27742591 Review.
Chromatin biology: Breaking into the PRC2 cage.
Holoch D, Margueron R. Holoch D, et al. Among authors: margueron r. Nat Chem Biol. 2017 Apr;13(4):345-346. doi: 10.1038/nchembio.2313. Epub 2017 Jan 30. Nat Chem Biol. 2017. PMID: 28135238 No abstract available.
PRC2 is dispensable for HOTAIR-mediated transcriptional repression.
Portoso M, Ragazzini R, Brenčič Ž, Moiani A, Michaud A, Vassilev I, Wassef M, Servant N, Sargueil B, Margueron R. Portoso M, et al. Among authors: margueron r. EMBO J. 2017 Apr 13;36(8):981-994. doi: 10.15252/embj.201695335. Epub 2017 Feb 6. EMBO J. 2017. PMID: 28167697 Free PMC article.
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