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Association analysis of 29,956 individuals confirms that a low-frequency variant at CCND2 halves the risk of type 2 diabetes by enhancing insulin secretion.
Yaghootkar H, Stancáková A, Freathy RM, Vangipurapu J, Weedon MN, Xie W, Wood AR, Ferrannini E, Mari A, Ring SM, Lawlor DA, Davey Smith G, Jørgensen T, Hansen T, Pedersen O, Steinthorsdottir V, Guðbjartsson DF, Thorleifsson G, Thorsteinsdottir U, Stefansson K, Hattersley AT, Walker M, Morris AD, McCarthy MI, Palmer CN, Laakso M, Frayling TM. Yaghootkar H, et al. Among authors: mari a. Diabetes. 2015 Jun;64(6):2279-85. doi: 10.2337/db14-1456. Epub 2015 Jan 20. Diabetes. 2015. PMID: 25605810 Free PMC article.
Effect of acute hyperglycemia on insulin secretion in humans.
Toschi E, Camastra S, Sironi AM, Masoni A, Gastaldelli A, Mari A, Ferrannini E, Natali A. Toschi E, et al. Among authors: mari a. Diabetes. 2002 Feb;51 Suppl 1:S130-3. doi: 10.2337/diabetes.51.2007.s130. Diabetes. 2002. PMID: 11815471 Clinical Trial.
beta-cell function in obesity: effects of weight loss.
Ferrannini E, Camastra S, Gastaldelli A, Maria Sironi A, Natali A, Muscelli E, Mingrone G, Mari A. Ferrannini E, et al. Among authors: mari a. Diabetes. 2004 Dec;53 Suppl 3:S26-33. doi: 10.2337/diabetes.53.suppl_3.s26. Diabetes. 2004. PMID: 15561918 Review.
1,136 results