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A transgenic rabbit model for human hypertrophic cardiomyopathy.
Marian AJ, Wu Y, Lim DS, McCluggage M, Youker K, Yu QT, Brugada R, DeMayo F, Quinones M, Roberts R. Marian AJ, et al. J Clin Invest. 1999 Dec;104(12):1683-92. doi: 10.1172/JCI7956. J Clin Invest. 1999. PMID: 10606622 Free PMC article.
Aldosterone, through novel signaling proteins, is a fundamental molecular bridge between the genetic defect and the cardiac phenotype of hypertrophic cardiomyopathy.
Tsybouleva N, Zhang L, Chen S, Patel R, Lutucuta S, Nemoto S, DeFreitas G, Entman M, Carabello BA, Roberts R, Marian AJ. Tsybouleva N, et al. Among authors: marian aj. Circulation. 2004 Mar 16;109(10):1284-91. doi: 10.1161/01.CIR.0000121426.43044.2B. Epub 2004 Mar 1. Circulation. 2004. PMID: 14993121 Free PMC article.
Transgenic mouse model of ventricular preexcitation and atrioventricular reentrant tachycardia induced by an AMP-activated protein kinase loss-of-function mutation responsible for Wolff-Parkinson-White syndrome.
Sidhu JS, Rajawat YS, Rami TG, Gollob MH, Wang Z, Yuan R, Marian AJ, DeMayo FJ, Weilbacher D, Taffet GE, Davies JK, Carling D, Khoury DS, Roberts R. Sidhu JS, et al. Among authors: marian aj. Circulation. 2005 Jan 4;111(1):21-9. doi: 10.1161/01.CIR.0000151291.32974.D5. Epub 2004 Dec 20. Circulation. 2005. PMID: 15611370 Free PMC article.
A common PCSK9 haplotype, encompassing the E670G coding single nucleotide polymorphism, is a novel genetic marker for plasma low-density lipoprotein cholesterol levels and severity of coronary atherosclerosis.
Chen SN, Ballantyne CM, Gotto AM Jr, Tan Y, Willerson JT, Marian AJ. Chen SN, et al. Among authors: marian aj. J Am Coll Cardiol. 2005 May 17;45(10):1611-9. doi: 10.1016/j.jacc.2005.01.051. Epub 2005 Apr 21. J Am Coll Cardiol. 2005. PMID: 15893176 Free PMC article. Clinical Trial.
228 results