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Prostate tumor-initiating cells: a new target for telomerase inhibition therapy?
Marian CO, Shay JW. Marian CO, et al. Biochim Biophys Acta. 2009 Apr;1792(4):289-96. doi: 10.1016/j.bbadis.2009.02.012. Epub 2009 Mar 2. Biochim Biophys Acta. 2009. PMID: 19264126 Free article. Review.
Evidence of epithelial to mesenchymal transition associated with increased tumorigenic potential in an immortalized normal prostate epithelial cell line.
Marian CO, Yang L, Zou YS, Gore C, Pong RC, Shay JW, Kabbani W, Hsieh JT, Raj GV. Marian CO, et al. Prostate. 2011 May;71(6):626-36. doi: 10.1002/pros.21278. Epub 2010 Oct 13. Prostate. 2011. PMID: 20945502
The telomerase antagonist, imetelstat, efficiently targets glioblastoma tumor-initiating cells leading to decreased proliferation and tumor growth.
Marian CO, Cho SK, McEllin BM, Maher EA, Hatanpaa KJ, Madden CJ, Mickey BE, Wright WE, Shay JW, Bachoo RM. Marian CO, et al. Clin Cancer Res. 2010 Jan 1;16(1):154-63. doi: 10.1158/1078-0432.CCR-09-2850. Clin Cancer Res. 2010. PMID: 20048334 Free PMC article.
The effects of telomerase inhibition on prostate tumor-initiating cells.
Marian CO, Wright WE, Shay JW. Marian CO, et al. Int J Cancer. 2010 Jul 15;127(2):321-31. doi: 10.1002/ijc.25043. Int J Cancer. 2010. PMID: 19908230 Free article.
The Terminal acidic SANT 1 (Tacs1) gene of maize is expressed in tissues containing meristems and encodes an acidic SANT domain similar to some chromatin-remodeling complex proteins.
Marian CO, Bass HW. Marian CO, et al. Biochim Biophys Acta. 2005 Feb 14;1727(2):81-6. doi: 10.1016/j.bbaexp.2004.12.010. Epub 2005 Jan 13. Biochim Biophys Acta. 2005. PMID: 15716051
The maize Single myb histone 1 gene, Smh1, belongs to a novel gene family and encodes a protein that binds telomere DNA repeats in vitro.
Marian CO, Bordoli SJ, Goltz M, Santarella RA, Jackson LP, Danilevskaya O, Beckstette M, Meeley R, Bass HW. Marian CO, et al. Plant Physiol. 2003 Nov;133(3):1336-50. doi: 10.1104/pp.103.026856. Epub 2003 Oct 23. Plant Physiol. 2003. PMID: 14576282 Free PMC article.
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