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Mechanisms of resistance to azole antifungals.
Marichal P, Vanden Bossche H. Marichal P, et al. Acta Biochim Pol. 1995;42(4):509-16. Acta Biochim Pol. 1995. PMID: 8852341 Review.
The novel azole R126638 is a selective inhibitor of ergosterol synthesis in Candida albicans, Trichophyton spp., and Microsporum canis.
Vanden Bossche H, Ausma J, Bohets H, Vermuyten K, Willemsens G, Marichal P, Meerpoel L, Odds F, Borgers M. Vanden Bossche H, et al. Among authors: Marichal P. Antimicrob Agents Chemother. 2004 Sep;48(9):3272-8. doi: 10.1128/AAC.48.9.3272-3278.2004. Antimicrob Agents Chemother. 2004. PMID: 15328084 Free PMC article.
Synthesis and in vitro and in vivo structure-activity relationships of novel antifungal triazoles for dermatology.
Meerpoel L, Backx LJ, Van der Veken LJ, Heeres J, Corens D, De Groot A, Odds FC, Van Gerven F, Woestenborghs FA, Van Breda A, Oris M, van Dorsselaer P, Willemsens GH, Vermuyten KJ, Marichal PJ, Vanden Bossche HF, Ausma J, Borgers M. Meerpoel L, et al. Among authors: Marichal PJ. J Med Chem. 2005 Mar 24;48(6):2184-93. doi: 10.1021/jm0494772. J Med Chem. 2005. PMID: 15771461
Synthesis and in vitro and in vivo antifungal activity of the hydroxy metabolites of saperconazole.
Meerpoel L, Heeres J, Backx LJ, Van der Veken LJ, Hendrickx R, Corens D, De Groot A, Leurs S, Van der Eycken L, Weerts J, Luyts P, Van Gerven F, Woestenborghs FA, Van Breda A, Oris M, van Dorsselaer P, Willemsens GH, Bellens D, Marichal PJ, Vanden Bossche HF, Odds FC. Meerpoel L, et al. Among authors: Marichal PJ. ChemMedChem. 2010 May 3;5(5):757-69. doi: 10.1002/cmdc.201000040. ChemMedChem. 2010. PMID: 20379992
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