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NVP-BEZ235, a dual PI3K/mTOR inhibitor, prevents PI3K signaling and inhibits the growth of cancer cells with activating PI3K mutations.
Serra V, Markman B, Scaltriti M, Eichhorn PJ, Valero V, Guzman M, Botero ML, Llonch E, Atzori F, Di Cosimo S, Maira M, Garcia-Echeverria C, Parra JL, Arribas J, Baselga J. Serra V, et al. Among authors: markman b. Cancer Res. 2008 Oct 1;68(19):8022-30. doi: 10.1158/0008-5472.CAN-08-1385. Cancer Res. 2008. PMID: 18829560
New approaches and targets in advanced colorectal cancer.
Macarulla T, Capdevila J, Perez-Garcia J, Ramos FJ, Elez ME, Markman B, Ruiz-Echarri M, Tabernero J. Macarulla T, et al. Among authors: markman b. Eur J Cancer. 2009 Sep;45 Suppl 1:79-88. doi: 10.1016/S0959-8049(09)70019-X. Eur J Cancer. 2009. PMID: 19775607 No abstract available.
Monoclonal antibodies in solid tumours.
Markman B, Tabernero J. Markman B, et al. Curr Clin Pharmacol. 2010 Aug;5(3):160-5. doi: 10.2174/157488410791498833. Curr Clin Pharmacol. 2010. PMID: 20406174 Review.
Biomarkers in colorectal cancer.
Markman B, Rodríguez-Freixinos V, Tabernero J. Markman B, et al. Clin Transl Oncol. 2010 Apr;12(4):261-70. doi: 10.1007/s12094-010-0502-z. Clin Transl Oncol. 2010. PMID: 20462835 Review.
EGFR and KRAS in colorectal cancer.
Markman B, Javier Ramos F, Capdevila J, Tabernero J. Markman B, et al. Adv Clin Chem. 2010;51:71-119. doi: 10.1016/s0065-2423(10)51004-7. Adv Clin Chem. 2010. PMID: 20857619 Review.
PI3K inhibition results in enhanced HER signaling and acquired ERK dependency in HER2-overexpressing breast cancer.
Serra V, Scaltriti M, Prudkin L, Eichhorn PJ, Ibrahim YH, Chandarlapaty S, Markman B, Rodriguez O, Guzman M, Rodriguez S, Gili M, Russillo M, Parra JL, Singh S, Arribas J, Rosen N, Baselga J. Serra V, et al. Among authors: markman b. Oncogene. 2011 Jun 2;30(22):2547-57. doi: 10.1038/onc.2010.626. Epub 2011 Jan 31. Oncogene. 2011. PMID: 21278786 Free PMC article.
72 results