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Diverging metabolic programmes and behaviours during states of starvation, protein malnutrition, and cachexia.
Olson B, Marks DL, Grossberg AJ. Olson B, et al. Among authors: marks dl. J Cachexia Sarcopenia Muscle. 2020 Sep 28. doi: 10.1002/jcsm.12630. Online ahead of print. J Cachexia Sarcopenia Muscle. 2020. PMID: 32985801 Free article. Review.
Effects on Mouse Food Consumption After Exposure to Bedding from Sick Mice or Healthy Mice.
Lovasz RM, Marks DL, Chan BK, Saunders KE. Lovasz RM, et al. Among authors: marks dl. J Am Assoc Lab Anim Sci. 2020 Aug 28. doi: 10.30802/AALAS-JAALAS-19-000154. Online ahead of print. J Am Assoc Lab Anim Sci. 2020. PMID: 32859281
Targeting of the Hedgehog/GLI and mTOR pathways in advanced pancreatic cancer, a phase 1 trial of Vismodegib and Sirolimus combination.
Carr RM, Duma N, McCleary-Wheeler AL, Almada LL, Marks DL, Graham RP, Smyrk TC, Lowe V, Borad MJ, Kim G, Johnson GB, Allred JB, Yin J, Lim VS, Bekaii-Saab T, Ma WW, Erlichman C, Adjei AA, Fernandez-Zapico ME. Carr RM, et al. Among authors: marks dl. Pancreatology. 2020 Sep;20(6):1115-1122. doi: 10.1016/j.pan.2020.06.015. Epub 2020 Jul 14. Pancreatology. 2020. PMID: 32778368
GLI1/GLI2 functional interplay is required to control Hedgehog/GLI targets gene expression.
Tolosa EJ, Fernandez-Barrena MG, Iguchi E, McCleary-Wheeler AL, Carr RM, Almada LL, Flores LF, Vera RE, Alfonse GW, Marks DL, Hogenson TL, Vrabel AM, Horn IP, Koenig AN, Safgren SL, Sigafoos AN, Erkan M, Romecin-Duran PA, Sarabia Gonzalez A, Zhou B, Javelaud D, Marsaud V, Graham RP, Mauviel A, Elsawa SF, Fernandez-Zapico ME. Tolosa EJ, et al. Among authors: marks dl. Biochem J. 2020 Sep 18;477(17):3131-3145. doi: 10.1042/BCJ20200335. Biochem J. 2020. PMID: 32766732
Multidisciplinary standards of care and recent progress in pancreatic ductal adenocarcinoma.
Grossberg AJ, Chu LC, Deig CR, Fishman EK, Hwang WL, Maitra A, Marks DL, Mehta A, Nabavizadeh N, Simeone DM, Weekes CD, Thomas CR Jr. Grossberg AJ, et al. Among authors: marks dl. CA Cancer J Clin. 2020 Jul 19. doi: 10.3322/caac.21626. Online ahead of print. CA Cancer J Clin. 2020. PMID: 32683683 Free article. Review.
TFII-I-mediated polymerase pausing antagonizes GLI2 induction by TGFβ.
McCleary-Wheeler AL, Paradise BD, Almada LL, Carlson AJ, Marks DL, Vrabel A, Vera RE, Sigafoos AN, Olson RL, Fernandez-Zapico ME. McCleary-Wheeler AL, et al. Among authors: marks dl. Nucleic Acids Res. 2020 Jul 27;48(13):7169-7181. doi: 10.1093/nar/gkaa476. Nucleic Acids Res. 2020. PMID: 32544250 Free PMC article.
Melanocortin-4 receptor antagonist TCMCB07 ameliorates cancer- and chronic kidney disease-associated cachexia.
Zhu X, Callahan MF, Gruber KA, Szumowski M, Marks DL. Zhu X, et al. Among authors: marks dl. J Clin Invest. 2020 Sep 1;130(9):4921-4934. doi: 10.1172/JCI138392. J Clin Invest. 2020. PMID: 32544087 Free article.
Leptin increases sympathetic nerve activity via induction of its own receptor in the paraventricular nucleus.
Shi Z, Pelletier NE, Wong J, Li B, Sdrulla AD, Madden CJ, Marks DL, Brooks VL. Shi Z, et al. Among authors: marks dl. Elife. 2020 Jun 15;9:e55357. doi: 10.7554/eLife.55357. Elife. 2020. PMID: 32538782 Free PMC article.
Association of Sarcopenia With Oncologic Outcomes of Primary Surgery or Definitive Radiotherapy Among Patients With Localized Oropharyngeal Squamous Cell Carcinoma.
Olson B, Edwards J, Stone L, Jiang A, Zhu X, Holland J, Li R, Andersen P, Krasnow S, Marks DL, Clayburgh D. Olson B, et al. Among authors: marks dl. JAMA Otolaryngol Head Neck Surg. 2020 Jun 11;146(8):1-9. doi: 10.1001/jamaoto.2020.1154. Online ahead of print. JAMA Otolaryngol Head Neck Surg. 2020. PMID: 32525518
Circulating myeloid cells invade the central nervous system to mediate cachexia during pancreatic cancer.
Burfeind KG, Zhu X, Norgard MA, Levasseur PR, Huisman C, Buenafe AC, Olson B, Michaelis KA, Torres ER, Jeng S, McWeeney S, Raber J, Marks DL. Burfeind KG, et al. Among authors: marks dl. Elife. 2020 May 11;9:e54095. doi: 10.7554/eLife.54095. Elife. 2020. PMID: 32391790 Free PMC article.
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