Age-related accumulation of pentosidine in aggrecan and collagen from normal and degenerate human intervertebral discs.
Sivan SS, Tsitron E, Wachtel E, Roughley P, Sakkee N, van der Ham F, Degroot J, Maroudas A.
Sivan SS, et al. Among authors: maroudas a.
Biochem J. 2006 Oct 1;399(1):29-35. doi: 10.1042/BJ20060579.
Biochem J. 2006.
PMID: 16787390
Free PMC article.
We found that, after maturity, pentosidine accumulates with age. Over the age range studied, a linear 6-fold increase was observed in pentosidine accumulation for A1 and collagen with respective rates of 0.12 and 0.66 nmol x (g of protein)(-1) x year(-1). Using previously …
We found that, after maturity, pentosidine accumulates with age. Over the age range studied, a linear 6-fold increase was observed in …