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DNA targeting specificity of RNA-guided Cas9 nucleases.
Hsu PD, Scott DA, Weinstein JA, Ran FA, Konermann S, Agarwala V, Li Y, Fine EJ, Wu X, Shalem O, Cradick TJ, Marraffini LA, Bao G, Zhang F. Hsu PD, et al. Among authors: marraffini la. Nat Biotechnol. 2013 Sep;31(9):827-32. doi: 10.1038/nbt.2647. Epub 2013 Jul 21. Nat Biotechnol. 2013. PMID: 23873081 Free PMC article.
Type III CRISPR-Cas: beyond the Cas10 effector complex.
Stella G, Marraffini L. Stella G, et al. Trends Biochem Sci. 2024 Jan;49(1):28-37. doi: 10.1016/j.tibs.2023.10.006. Epub 2023 Nov 8. Trends Biochem Sci. 2024. PMID: 37949766 Free article. Review.
Multiplex genome engineering using CRISPR/Cas systems.
Cong L, Ran FA, Cox D, Lin S, Barretto R, Habib N, Hsu PD, Wu X, Jiang W, Marraffini LA, Zhang F. Cong L, et al. Among authors: marraffini la. Science. 2013 Feb 15;339(6121):819-23. doi: 10.1126/science.1231143. Epub 2013 Jan 3. Science. 2013. PMID: 23287718 Free PMC article.
RNA-guided editing of bacterial genomes using CRISPR-Cas systems.
Jiang W, Bikard D, Cox D, Zhang F, Marraffini LA. Jiang W, et al. Among authors: marraffini la. Nat Biotechnol. 2013 Mar;31(3):233-9. doi: 10.1038/nbt.2508. Epub 2013 Jan 29. Nat Biotechnol. 2013. PMID: 23360965 Free PMC article.
Exploiting CRISPR-Cas nucleases to produce sequence-specific antimicrobials.
Bikard D, Euler CW, Jiang W, Nussenzweig PM, Goldberg GW, Duportet X, Fischetti VA, Marraffini LA. Bikard D, et al. Among authors: marraffini la. Nat Biotechnol. 2014 Nov;32(11):1146-50. doi: 10.1038/nbt.3043. Epub 2014 Oct 5. Nat Biotechnol. 2014. PMID: 25282355 Free PMC article.
Cas9 specifies functional viral targets during CRISPR-Cas adaptation.
Heler R, Samai P, Modell JW, Weiner C, Goldberg GW, Bikard D, Marraffini LA. Heler R, et al. Among authors: marraffini la. Nature. 2015 Mar 12;519(7542):199-202. doi: 10.1038/nature14245. Epub 2015 Feb 18. Nature. 2015. PMID: 25707807 Free PMC article.
90 results