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A TMPRSS2 inhibitor acts as a pan-SARS-CoV-2 prophylactic and therapeutic.
Shapira T, Monreal IA, Dion SP, Buchholz DW, Imbiakha B, Olmstead AD, Jager M, Désilets A, Gao G, Martins M, Vandal T, Thompson CAH, Chin A, Rees WD, Steiner T, Nabi IR, Marsault E, Sahler J, Diel DG, Van de Walle GR, August A, Whittaker GR, Boudreault PL, Leduc R, Aguilar HC, Jean F. Shapira T, et al. Among authors: marsault e. Nature. 2022 May;605(7909):340-348. doi: 10.1038/s41586-022-04661-w. Epub 2022 Mar 28. Nature. 2022. PMID: 35344983 Free PMC article.
Design and synthesis of potent, selective inhibitors of matriptase.
Colombo E, Désilets A, Duchêne D, Chagnon F, Najmanovich R, Leduc R, Marsault E. Colombo E, et al. Among authors: marsault e. ACS Med Chem Lett. 2012 Apr 11;3(7):530-4. doi: 10.1021/ml3000534. eCollection 2012 Jul 12. ACS Med Chem Lett. 2012. PMID: 24900505 Free PMC article.
Design, synthesis, and biological evaluation of CXCR4 ligands.
Mona CE, Besserer-Offroy É, Cabana J, Leduc R, Lavigne P, Heveker N, Marsault É, Escher E. Mona CE, et al. Among authors: marsault e. Org Biomol Chem. 2016 Nov 2;14(43):10298-10311. doi: 10.1039/c6ob01484d. Org Biomol Chem. 2016. PMID: 27752700
Modulating the selectivity of matriptase-2 inhibitors with unnatural amino acids.
St-Georges C, Désilets A, Béliveau F, Ghinet M, Dion SP, Colombo É, Boudreault PL, Najmanovich RJ, Leduc R, Marsault É. St-Georges C, et al. Among authors: marsault e. Eur J Med Chem. 2017 Mar 31;129:110-123. doi: 10.1016/j.ejmech.2017.02.006. Epub 2017 Feb 11. Eur J Med Chem. 2017. PMID: 28219045
In Search of the Optimal Macrocyclization Site for Neurotensin.
Sousbie M, Besserer-Offroy É, Brouillette RL, Longpré JM, Leduc R, Sarret P, Marsault É. Sousbie M, et al. Among authors: marsault e. ACS Med Chem Lett. 2018 Jan 29;9(3):227-232. doi: 10.1021/acsmedchemlett.7b00500. eCollection 2018 Mar 8. ACS Med Chem Lett. 2018. PMID: 29541365 Free PMC article.
77 results