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Tolling for autoimmunity-prime time for 7.
Marshak-Rothstein A. Marshak-Rothstein A. Immunity. 2006 Sep;25(3):397-9. doi: 10.1016/j.immuni.2006.08.011. Immunity. 2006. PMID: 16979573 Free article.
Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE.
Tian J, Avalos AM, Mao SY, Chen B, Senthil K, Wu H, Parroche P, Drabic S, Golenbock D, Sirois C, Hua J, An LL, Audoly L, La Rosa G, Bierhaus A, Naworth P, Marshak-Rothstein A, Crow MK, Fitzgerald KA, Latz E, Kiener PA, Coyle AJ. Tian J, et al. Nat Immunol. 2007 May;8(5):487-96. doi: 10.1038/ni1457. Epub 2007 Apr 8. Nat Immunol. 2007. PMID: 17417641
Murine B cell response to TLR7 ligands depends on an IFN-beta feedback loop.
Green NM, Laws A, Kiefer K, Busconi L, Kim YM, Brinkmann MM, Trail EH, Yasuda K, Christensen SR, Shlomchik MJ, Vogel S, Connor JH, Ploegh H, Eilat D, Rifkin IR, van Seventer JM, Marshak-Rothstein A. Green NM, et al. J Immunol. 2009 Aug 1;183(3):1569-76. doi: 10.4049/jimmunol.0803899. Epub 2009 Jul 8. J Immunol. 2009. PMID: 19587008 Free PMC article.
The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation.
Franklin BS, Bossaller L, De Nardo D, Ratter JM, Stutz A, Engels G, Brenker C, Nordhoff M, Mirandola SR, Al-Amoudi A, Mangan MS, Zimmer S, Monks BG, Fricke M, Schmidt RE, Espevik T, Jones B, Jarnicki AG, Hansbro PM, Busto P, Marshak-Rothstein A, Hornemann S, Aguzzi A, Kastenmüller W, Latz E. Franklin BS, et al. Nat Immunol. 2014 Aug;15(8):727-37. doi: 10.1038/ni.2913. Epub 2014 Jun 22. Nat Immunol. 2014. PMID: 24952505 Free PMC article.
183 results