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Glucosamine-induced activation of glycogen biosynthesis in isolated adipocytes. Evidence for a rapid allosteric control mechanism within the hexosamine biosynthesis pathway.
Marshall S, Nadeau O, Yamasaki K. Marshall S, et al. J Biol Chem. 2005 Mar 25;280(12):11018-24. doi: 10.1074/jbc.M413499200. Epub 2005 Jan 12. J Biol Chem. 2005. PMID: 15647256
Potential regulation of nuclear UDP-N-acetylglucosaminyl transferase (OGT) by substrate availability: ability of chromatin protein to bind UDP-N-acetylglucosamine and reduce OGT-mediated O-Linked glycosylation.
Okuyama R, Marshall S. Okuyama R, et al. Biol Pharm Bull. 2004 Aug;27(8):1293-6. doi: 10.1248/bpb.27.1293. Biol Pharm Bull. 2004. PMID: 15305040
Dynamic actions of glucose and glucosamine on hexosamine biosynthesis in isolated adipocytes: differential effects on glucosamine 6-phosphate, UDP-N-acetylglucosamine, and ATP levels.
Marshall S, Nadeau O, Yamasaki K. Marshall S, et al. J Biol Chem. 2004 Aug 20;279(34):35313-9. doi: 10.1074/jbc.M404133200. Epub 2004 Jun 15. J Biol Chem. 2004. PMID: 15199059
Differential effects of vanadate on UDP-N-acetylglucosaminyl transferase activity derived from cytosol and nucleosol.
Marshall S, Okuyama R. Marshall S, et al. Biochem Biophys Res Commun. 2004 Jun 11;318(4):911-5. doi: 10.1016/j.bbrc.2004.04.101. Biochem Biophys Res Commun. 2004. PMID: 15147958
Understanding the mechanism(s) by which a tyrosine phosphatase inhibitor differentially reduces OGT activity should lead to new insights into OGT function and regulation....
Understanding the mechanism(s) by which a tyrosine phosphatase inhibitor differentially reduces OGT activity should lead to new insig …
UDP-N-acetylglucosaminyl transferase (OGT) in brain tissue: temperature sensitivity and subcellular distribution of cytosolic and nuclear enzyme.
Okuyama R, Marshall S. Okuyama R, et al. J Neurochem. 2003 Sep;86(5):1271-80. doi: 10.1046/j.1471-4159.2003.01939.x. J Neurochem. 2003. PMID: 12911634
Since a greater understanding of brain OGT may provide new insights into the pathogenesis of Alzheimer's disease, we examined the characteristics and subcellular distribution of OGT protein and OGT activity and its relationship to O-linked glycosylation. ...
Since a greater understanding of brain OGT may provide new insights into the pathogenesis of Alzheimer's disease, we examined the cha …
Enhanced expression of uridine diphosphate-N-acetylglucosaminyl transferase (OGT) in a stable, tetracycline-inducible HeLa cell line using histone deacetylase inhibitors: kinetics of cytosolic OGT accumulation and nuclear translocation.
Marshall S, Duong T, Wu T, Hering MA, Yada J, Higgins S, Orbus RJ, Yan ZH, Rumberger JM. Marshall S, et al. Anal Biochem. 2003 Aug 15;319(2):304-13. doi: 10.1016/s0003-2697(03)00329-4. Anal Biochem. 2003. PMID: 12871726
The ability to rapidly induce OGT expression in a stable cell line provides an excellent model system to study the mechanism(s) underlying OGT nuclear translocation and a useful system to elucidate the cascade of signaling events related to O-linked glycosylation....
The ability to rapidly induce OGT expression in a stable cell line provides an excellent model system to study the mechanism(s) under …
Role of hexosamine biosynthesis in glucose-mediated up-regulation of lipogenic enzyme mRNA levels: effects of glucose, glutamine, and glucosamine on glycerophosphate dehydrogenase, fatty acid synthase, and acetyl-CoA carboxylase mRNA levels.
Rumberger JM, Wu T, Hering MA, Marshall S. Rumberger JM, et al. J Biol Chem. 2003 Aug 1;278(31):28547-52. doi: 10.1074/jbc.M302793200. Epub 2003 May 20. J Biol Chem. 2003. PMID: 12759350
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