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76 results
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Imaging Mutant Huntingtin Aggregates: Development of a Potential PET ligand.
Liu L, Prime ME, Lee MR, Khetarpal V, Brown CJ, Johnson PD, Azpiazu P, Chen A, Clark-Frew D, Coe S, Davis R, Dickie A, Ebneth A, Esposito S, Gadouleau E, Gai X, Galan S, Green S, Greenaway C, Giles P, Halldin C, Hayes S, Herbst T, Herrmann F, Hessmann M, Jia Z, Kiselyov A, Kotey A, Krulle T, Mangette JE, Marston RW, Menta S, Mills MR, Monteagudo E, Nag S, Nibbio M, Orsatti L, Schaertl S, Scheich C, Sproston J, Stepanov V, Svedberg M, Takano A, Taylor M, Thomas W, Toth M, Vaidya D, Varnas K, Weddell D, Wigginton I, Wityak J, Mrzljak L, Muñoz-Sanjuan I, Bard JA, Dominguez C. Liu L, et al. Among authors: marston rw. J Med Chem. 2020 Jul 14. doi: 10.1021/acs.jmedchem.0c00955. Online ahead of print. J Med Chem. 2020. PMID: 32662649
Recent global decline in endorheic basin water storages.
Wang J, Song C, Reager JT, Yao F, Famiglietti JS, Sheng Y, MacDonald GM, Brun F, Schmied HM, Marston RA, Wada Y. Wang J, et al. Among authors: marston ra. Nat Geosci. 2018;11:926-932. doi: 10.1038/s41561-018-0265-7. Epub 2018 Nov 30. Nat Geosci. 2018. PMID: 30510596 Free PMC article. No abstract available.
Older UK sheltered housing tenants' perceptions of well-being and their usage of hospital services.
Cook G, Bailey C, Hodgson P, Gray J, Barron E, McMillan C, Marston R, Binks E, Rose J. Cook G, et al. Among authors: marston r. Health Soc Care Community. 2017 Sep;25(5):1644-1654. doi: 10.1111/hsc.12398. Epub 2016 Oct 10. Health Soc Care Community. 2017. PMID: 27723175
SAR Development of Lysine-Based Irreversible Inhibitors of Transglutaminase 2 for Huntington's Disease.
Wityak J, Prime ME, Brookfield FA, Courtney SM, Erfan S, Johnsen S, Johnson PD, Li M, Marston RW, Reed L, Vaidya D, Schaertl S, Pedret-Dunn A, Beconi M, Macdonald D, Muñoz-Sanjuan I, Dominguez C. Wityak J, et al. Among authors: marston rw. ACS Med Chem Lett. 2012 Oct 4;3(12):1024-8. doi: 10.1021/ml300241m. eCollection 2012 Dec 13. ACS Med Chem Lett. 2012. PMID: 24900424 Free PMC article.
Irreversible 4-Aminopiperidine Transglutaminase 2 Inhibitors for Huntington's Disease.
Prime ME, Brookfield FA, Courtney SM, Gaines S, Marston RW, Ichihara O, Li M, Vaidya D, Williams H, Pedret-Dunn A, Reed L, Schaertl S, Toledo-Sherman L, Beconi M, Macdonald D, Muñoz-Sanjuan I, Dominguez C, Wityak J. Prime ME, et al. Among authors: marston rw. ACS Med Chem Lett. 2012 Aug 9;3(9):731-5. doi: 10.1021/ml3001352. eCollection 2012 Sep 13. ACS Med Chem Lett. 2012. PMID: 24900540 Free PMC article.
Discovery and structure-activity relationship of potent and selective covalent inhibitors of transglutaminase 2 for Huntington's disease.
Prime ME, Andersen OA, Barker JJ, Brooks MA, Cheng RK, Toogood-Johnson I, Courtney SM, Brookfield FA, Yarnold CJ, Marston RW, Johnson PD, Johnsen SF, Palfrey JJ, Vaidya D, Erfan S, Ichihara O, Felicetti B, Palan S, Pedret-Dunn A, Schaertl S, Sternberger I, Ebneth A, Scheel A, Winkler D, Toledo-Sherman L, Beconi M, Macdonald D, Muñoz-Sanjuan I, Dominguez C, Wityak J. Prime ME, et al. Among authors: marston rw. J Med Chem. 2012 Feb 9;55(3):1021-46. doi: 10.1021/jm201310y. Epub 2012 Jan 27. J Med Chem. 2012. PMID: 22224594
Phthalazinone pyrazoles as potent, selective, and orally bioavailable inhibitors of Aurora-A kinase.
Prime ME, Courtney SM, Brookfield FA, Marston RW, Walker V, Warne J, Boyd AE, Kairies NA, von der Saal W, Limberg A, Georges G, Engh RA, Goller B, Rueger P, Rueth M. Prime ME, et al. Among authors: marston rw. J Med Chem. 2011 Jan 13;54(1):312-9. doi: 10.1021/jm101346r. Epub 2010 Dec 3. J Med Chem. 2011. PMID: 21128645
Malignant hyperthermia associated with exercise-induced rhabdomyolysis or congenital abnormalities and a novel RYR1 mutation in New Zealand and Australian pedigrees.
Davis M, Brown R, Dickson A, Horton H, James D, Laing N, Marston R, Norgate M, Perlman D, Pollock N, Stowell K. Davis M, et al. Among authors: marston r. Br J Anaesth. 2002 Apr;88(4):508-15. doi: 10.1093/bja/88.4.508. Br J Anaesth. 2002. PMID: 12066726 Free article.
Lawyers out of hospitals, doctors out of court.
Marston RA. Marston RA. Ann R Coll Surg Engl. 1998 Nov;80(6 Suppl):299. Ann R Coll Surg Engl. 1998. PMID: 10343564 No abstract available.
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