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Page 1
Highly accurate protein structure prediction with AlphaFold.
Jumper J, Evans R, Pritzel A, Green T, Figurnov M, Ronneberger O, Tunyasuvunakool K, Bates R, Žídek A, Potapenko A, Bridgland A, Meyer C, Kohl SAA, Ballard AJ, Cowie A, Romera-Paredes B, Nikolov S, Jain R, Adler J, Back T, Petersen S, Reiman D, Clancy E, Zielinski M, Steinegger M, Pacholska M, Berghammer T, Bodenstein S, Silver D, Vinyals O, Senior AW, Kavukcuoglu K, Kohli P, Hassabis D. Jumper J, et al. Among authors: steinegger m. Nature. 2021 Aug;596(7873):583-589. doi: 10.1038/s41586-021-03819-2. Epub 2021 Jul 15. Nature. 2021. PMID: 34265844 Free PMC article.
Metagenome analysis using the Kraken software suite.
Lu J, Rincon N, Wood DE, Breitwieser FP, Pockrandt C, Langmead B, Salzberg SL, Steinegger M. Lu J, et al. Among authors: steinegger m. Nat Protoc. 2022 Dec;17(12):2815-2839. doi: 10.1038/s41596-022-00738-y. Epub 2022 Sep 28. Nat Protoc. 2022. PMID: 36171387 Free PMC article. Review.
ProtTrans: Toward Understanding the Language of Life Through Self-Supervised Learning.
Elnaggar A, Heinzinger M, Dallago C, Rehawi G, Wang Y, Jones L, Gibbs T, Feher T, Angerer C, Steinegger M, Bhowmik D, Rost B. Elnaggar A, et al. Among authors: steinegger m. IEEE Trans Pattern Anal Mach Intell. 2022 Oct;44(10):7112-7127. doi: 10.1109/TPAMI.2021.3095381. Epub 2022 Sep 14. IEEE Trans Pattern Anal Mach Intell. 2022. PMID: 34232869
ColabFold: making protein folding accessible to all.
Mirdita M, Schütze K, Moriwaki Y, Heo L, Ovchinnikov S, Steinegger M. Mirdita M, et al. Among authors: steinegger m. Nat Methods. 2022 Jun;19(6):679-682. doi: 10.1038/s41592-022-01488-1. Epub 2022 May 30. Nat Methods. 2022. PMID: 35637307 Free PMC article.
Fast and accurate protein structure search with Foldseek.
van Kempen M, Kim SS, Tumescheit C, Mirdita M, Lee J, Gilchrist CLM, Söding J, Steinegger M. van Kempen M, et al. Among authors: steinegger m. Nat Biotechnol. 2024 Feb;42(2):243-246. doi: 10.1038/s41587-023-01773-0. Epub 2023 May 8. Nat Biotechnol. 2024. PMID: 37156916 Free PMC article.
Clustering predicted structures at the scale of the known protein universe.
Barrio-Hernandez I, Yeo J, Jänes J, Mirdita M, Gilchrist CLM, Wein T, Varadi M, Velankar S, Beltrao P, Steinegger M. Barrio-Hernandez I, et al. Among authors: steinegger m. Nature. 2023 Oct;622(7983):637-645. doi: 10.1038/s41586-023-06510-w. Epub 2023 Sep 13. Nature. 2023. PMID: 37704730 Free PMC article.
AlphaFold Protein Structure Database in 2024: providing structure coverage for over 214 million protein sequences.
Varadi M, Bertoni D, Magana P, Paramval U, Pidruchna I, Radhakrishnan M, Tsenkov M, Nair S, Mirdita M, Yeo J, Kovalevskiy O, Tunyasuvunakool K, Laydon A, Žídek A, Tomlinson H, Hariharan D, Abrahamson J, Green T, Jumper J, Birney E, Steinegger M, Hassabis D, Velankar S. Varadi M, et al. Among authors: steinegger m. Nucleic Acids Res. 2024 Jan 5;52(D1):D368-D375. doi: 10.1093/nar/gkad1011. Nucleic Acids Res. 2024. PMID: 37933859 Free PMC article.
Mutation-induced LZTR1 polymerization provokes cardiac pathology in recessive Noonan syndrome.
Busley AV, Gutiérrez-Gutiérrez Ó, Hammer E, Koitka F, Mirzaiebadizi A, Steinegger M, Pape C, Böhmer L, Schroeder H, Kleinsorge M, Engler M, Cirstea IC, Gremer L, Willbold D, Altmüller J, Marbach F, Hasenfuss G, Zimmermann WH, Ahmadian MR, Wollnik B, Cyganek L. Busley AV, et al. Among authors: steinegger m. Cell Rep. 2024 Jul 23;43(7):114448. doi: 10.1016/j.celrep.2024.114448. Epub 2024 Jul 13. Cell Rep. 2024. PMID: 39003740 Free article.
Petabase-Scale Homology Search for Structure Prediction.
Lee S, Kim G, Karin EL, Mirdita M, Park S, Chikhi R, Babaian A, Kryshtafovych A, Steinegger M. Lee S, et al. Among authors: steinegger m. Cold Spring Harb Perspect Biol. 2024 May 2;16(5):a041465. doi: 10.1101/cshperspect.a041465. Cold Spring Harb Perspect Biol. 2024. PMID: 38316555 Review.
Easy and accurate protein structure prediction using ColabFold.
Kim G, Lee S, Levy Karin E, Kim H, Moriwaki Y, Ovchinnikov S, Steinegger M, Mirdita M. Kim G, et al. Among authors: steinegger m. Nat Protoc. 2025 Mar;20(3):620-642. doi: 10.1038/s41596-024-01060-5. Epub 2024 Oct 14. Nat Protoc. 2025. PMID: 39402428 Review.
57 results