Martin AP - Search Results

1

Inhibition of MCL-1 in breast cancer cells promotes cell death in vitro and in vivo.

Mitchell C, Yacoub A, Hossein H, Martin AP, Bareford MD, Eulitt P, Yang C, Nephew KP, Dent P. Mitchell C, et al. Among authors: martin ap. Cancer Biol Ther. 2010 Nov 1;10(9):903-17. doi: 10.4161/cbt.10.9.13273. Epub 2010 Nov 1. Cancer Biol Ther. 2010. PMID: 20855960 Free PMC article.

2

Human chorionic gonadotropin (hCG) interacts with lovastatin and ionizing radiation to modulate prostate cancer cell viability in vivo.

Hamed H, Mitchell C, Park MA, Hanna D, Martin AP, Harrison B, Hawkins W, Curiel DA, Fisher PB, Grant S, Yacoub A, Hagan MP, Dent P. Hamed H, et al. Among authors: martin ap. Cancer Biol Ther. 2008 Apr;7(4):587-93. doi: 10.4161/cbt.7.4.5543. Epub 2008 Jan 8. Cancer Biol Ther. 2008. PMID: 18379195

3

Lapatinib resistance in HCT116 cells is mediated by elevated MCL-1 expression and decreased BAK activation and not by ERBB receptor kinase mutation.

Martin AP, Miller A, Emad L, Rahmani M, Walker T, Mitchell C, Hagan MP, Park MA, Yacoub A, Fisher PB, Grant S, Dent P. Martin AP, et al. Mol Pharmacol. 2008 Sep;74(3):807-22. doi: 10.1124/mol.108.047365. Epub 2008 Jun 10. Mol Pharmacol. 2008. PMID: 18544666 Free PMC article.

4

Inhibition of MCL-1 enhances lapatinib toxicity and overcomes lapatinib resistance via BAK-dependent autophagy.

Martin AP, Mitchell C, Rahmani M, Nephew KP, Grant S, Dent P. Martin AP, et al. Cancer Biol Ther. 2009 Nov;8(21):2084-96. doi: 10.4161/cbt.8.21.9895. Epub 2009 Nov 21. Cancer Biol Ther. 2009. PMID: 19823038 Free PMC article.

5

Vorinostat and sorafenib synergistically kill tumor cells via FLIP suppression and CD95 activation.

Zhang G, Park MA, Mitchell C, Hamed H, Rahmani M, Martin AP, Curiel DT, Yacoub A, Graf M, Lee R, Roberts JD, Fisher PB, Grant S, Dent P. Zhang G, et al. Among authors: martin ap. Clin Cancer Res. 2008 Sep 1;14(17):5385-99. doi: 10.1158/1078-0432.CCR-08-0469. Clin Cancer Res. 2008. PMID: 18765530 Free PMC article.

6

Vorinostat and sorafenib increase ER stress, autophagy and apoptosis via ceramide-dependent CD95 and PERK activation.

Park MA, Zhang G, Martin AP, Hamed H, Mitchell C, Hylemon PB, Graf M, Rahmani M, Ryan K, Liu X, Spiegel S, Norris J, Fisher PB, Grant S, Dent P. Park MA, et al. Among authors: martin ap. Cancer Biol Ther. 2008 Oct;7(10):1648-62. doi: 10.4161/cbt.7.10.6623. Epub 2008 Oct 12. Cancer Biol Ther. 2008. PMID: 18787411 Free PMC article.

7

MDA-7/IL-24-induced cell killing in malignant renal carcinoma cells occurs by a ceramide/CD95/PERK-dependent mechanism.

Park MA, Walker T, Martin AP, Allegood J, Vozhilla N, Emdad L, Sarkar D, Rahmani M, Graf M, Yacoub A, Koumenis C, Spiegel S, Curiel DT, Voelkel-Johnson C, Grant S, Fisher PB, Dent P. Park MA, et al. Among authors: martin ap. Mol Cancer Ther. 2009 May;8(5):1280-91. doi: 10.1158/1535-7163.MCT-09-0073. Epub 2009 May 5. Mol Cancer Ther. 2009. PMID: 19417161 Free PMC article.

8

BCL-2 family inhibitors enhance histone deacetylase inhibitor and sorafenib lethality via autophagy and overcome blockade of the extrinsic pathway to facilitate killing.

Martin AP, Park MA, Mitchell C, Walker T, Rahmani M, Thorburn A, Häussinger D, Reinehr R, Grant S, Dent P. Martin AP, et al. Mol Pharmacol. 2009 Aug;76(2):327-41. doi: 10.1124/mol.109.056309. Epub 2009 May 29. Mol Pharmacol. 2009. PMID: 19483105 Free PMC article.

9

Temporal dynamics and stoichiometry in human Notch signaling from Notch synaptic complex formation to nuclear entry of the Notch intracellular domain.

Tveriakhina L, Scanavachi G, Egan ED, Da Cunha Correia RB, Martin AP, Rogers JM, Yodh JS, Aster JC, Kirchhausen T, Blacklow SC. Tveriakhina L, et al. Among authors: martin ap. Dev Cell. 2024 Mar 29:S1534-5807(24)00189-8. doi: 10.1016/j.devcel.2024.03.021. Online ahead of print. Dev Cell. 2024. PMID: 38574735

10

Drahos J, Boateng-Kuffour A, Calvert M, Levine L, Dongha N, Li N, Pakbaz Z, Shah F, Martin AP. Drahos J, et al. Among authors: martin ap. Patient. 2024 Mar 26. doi: 10.1007/s40271-024-00678-7. Online ahead of print. Patient. 2024. PMID: 38530509

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