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Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth.
Bruchard M, Mignot G, Derangère V, Chalmin F, Chevriaux A, Végran F, Boireau W, Simon B, Ryffel B, Connat JL, Kanellopoulos J, Martin F, Rébé C, Apetoh L, Ghiringhelli F. Bruchard M, et al. Among authors: martin f. Nat Med. 2013 Jan;19(1):57-64. doi: 10.1038/nm.2999. Epub 2012 Dec 2. Nat Med. 2013. PMID: 23202296
Prognostic role of FOXP3+ regulatory T cells infiltrating human carcinomas: the paradox of colorectal cancer.
Ladoire S, Martin F, Ghiringhelli F. Ladoire S, et al. Among authors: martin f. Cancer Immunol Immunother. 2011 Jul;60(7):909-18. doi: 10.1007/s00262-011-1046-y. Epub 2011 Jun 5. Cancer Immunol Immunother. 2011. PMID: 21644034 Review.
In situ immune response after neoadjuvant chemotherapy for breast cancer predicts survival.
Ladoire S, Mignot G, Dabakuyo S, Arnould L, Apetoh L, Rébé C, Coudert B, Martin F, Bizollon MH, Vanoli A, Coutant C, Fumoleau P, Bonnetain F, Ghiringhelli F. Ladoire S, et al. Among authors: martin f. J Pathol. 2011 Jul;224(3):389-400. doi: 10.1002/path.2866. Epub 2011 Mar 25. J Pathol. 2011. PMID: 21437909
Cancer chemotherapy: not only a direct cytotoxic effect, but also an adjuvant for antitumor immunity.
Ménard C, Martin F, Apetoh L, Bouyer F, Ghiringhelli F. Ménard C, et al. Among authors: martin f. Cancer Immunol Immunother. 2008 Nov;57(11):1579-87. doi: 10.1007/s00262-008-0505-6. Epub 2008 Mar 28. Cancer Immunol Immunother. 2008. PMID: 18369619 Review.
Tumor infiltration by Tbet+ effector T cells and CD20+ B cells is associated with survival in gastric cancer patients.
Hennequin A, Derangère V, Boidot R, Apetoh L, Vincent J, Orry D, Fraisse J, Causeret S, Martin F, Arnould L, Beltjens F, Ghiringhelli F, Ladoire S. Hennequin A, et al. Among authors: martin f. Oncoimmunology. 2015 Jun 3;5(2):e1054598. doi: 10.1080/2162402X.2015.1054598. eCollection 2016 Feb. Oncoimmunology. 2015. PMID: 27057426 Free PMC article.
[Th9 cells: a new population of helper T cells].
Vegran F, Martin F, Apetoh L, Ghiringhelli F. Vegran F, et al. Among authors: martin f. Med Sci (Paris). 2016 Apr;32(4):387-93. doi: 10.1051/medsci/20163204017. Epub 2016 May 2. Med Sci (Paris). 2016. PMID: 27137696 Review. French.
5-Fluorouracil selectively kills tumor-associated myeloid-derived suppressor cells resulting in enhanced T cell-dependent antitumor immunity.
Vincent J, Mignot G, Chalmin F, Ladoire S, Bruchard M, Chevriaux A, Martin F, Apetoh L, Rébé C, Ghiringhelli F. Vincent J, et al. Among authors: martin f. Cancer Res. 2010 Apr 15;70(8):3052-61. doi: 10.1158/0008-5472.CAN-09-3690. Epub 2010 Apr 13. Cancer Res. 2010. PMID: 20388795
Controversies on the role of Th17 in cancer: a TGF-β-dependent immunosuppressive activity?
Martin F, Apetoh L, Ghiringhelli F. Martin F, et al. Trends Mol Med. 2012 Dec;18(12):742-9. doi: 10.1016/j.molmed.2012.09.007. Epub 2012 Oct 17. Trends Mol Med. 2012. PMID: 23083809 Review.
Membrane-associated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells.
Chalmin F, Ladoire S, Mignot G, Vincent J, Bruchard M, Remy-Martin JP, Boireau W, Rouleau A, Simon B, Lanneau D, De Thonel A, Multhoff G, Hamman A, Martin F, Chauffert B, Solary E, Zitvogel L, Garrido C, Ryffel B, Borg C, Apetoh L, Rébé C, Ghiringhelli F. Chalmin F, et al. Among authors: martin f. J Clin Invest. 2010 Feb;120(2):457-71. doi: 10.1172/JCI40483. Epub 2010 Jan 19. J Clin Invest. 2010. PMID: 20093776 Free PMC article.
DNA-damaged polyploid cancer cells can reverse to diploidy: an ordered, but little understood, process of genomic reduction [with reference to the previous comments of Forer (2008) and Wheatley (2008a and b)].
Martin F, Puig PE, Ghiringhelli F, Chauffert B. Martin F, et al. Cell Biol Int. 2009 Jun;33(6):702-3. doi: 10.1016/j.cellbi.2009.02.016. Epub 2009 Mar 19. Cell Biol Int. 2009. PMID: 19303938 No abstract available.
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