Martin PD - Search Results

1

An open-label, randomized, three-way crossover trial of the effects of coadministration of rosuvastatin and fenofibrate on the pharmacokinetic properties of rosuvastatin and fenofibric acid in healthy male volunteers.

Martin PD, Dane AL, Schneck DW, Warwick MJ. Martin PD, et al. Clin Ther. 2003 Feb;25(2):459-71. doi: 10.1016/s0149-2918(03)80089-9. Clin Ther. 2003. PMID: 12749507 Clinical Trial.

2

Effects of Fostamatinib on the Pharmacokinetics of Oral Contraceptive, Warfarin, and the Statins Rosuvastatin and Simvastatin: Results From Phase I Clinical Studies.

Martin P, Gillen M, Ritter J, Mathews D, Brealey C, Surry D, Oliver S, Holmes V, Severin P, Elsby R. Martin P, et al. Drugs R D. 2016 Mar;16(1):93-107. doi: 10.1007/s40268-015-0120-x. Drugs R D. 2016. PMID: 26748647 Free PMC article. Clinical Trial.

3

Pharmacokinetics of vandetanib: three phase I studies in healthy subjects.

Martin P, Oliver S, Kennedy SJ, Partridge E, Hutchison M, Clarke D, Giles P. Martin P, et al. Clin Ther. 2012 Jan;34(1):221-37. doi: 10.1016/j.clinthera.2011.11.011. Epub 2011 Dec 28. Clin Ther. 2012. PMID: 22206795 Clinical Trial.

4

Effects of Fostamatinib on the Pharmacokinetics of Digoxin (a P-Glycoprotein Substrate): Results From in Vitro and Phase I Clinical Studies.

Martin P, Gillen M, Millson D, Oliver S, Brealey C, Elsby R, Baluom M, Lau D, Mant T. Martin P, et al. Clin Ther. 2015 Dec 1;37(12):2811-22. doi: 10.1016/j.clinthera.2015.09.018. Epub 2015 Oct 26. Clin Ther. 2015. PMID: 26514315 Clinical Trial.

5

Evaluation of the Effect of Selumetinib on Cardiac Repolarization: A Randomized, Placebo- and Positive-controlled Crossover QT/QTc Study in Healthy Subjects.

Zhou D, So K, Dymond AW, Vik T, Al-Huniti N, Mariani G, Zorenyi G, Huang Y, Holmes V, Severin P, Rasmussen S, Martin P. Zhou D, et al. Clin Ther. 2016 Dec;38(12):2555-2566. doi: 10.1016/j.clinthera.2016.10.004. Epub 2016 Nov 9. Clin Ther. 2016. PMID: 27837934 Clinical Trial.

6

Metabolism, Excretion, and Pharmacokinetics of Selumetinib, an MEK1/2 inhibitor, in Healthy Adult Male Subjects.

Dymond AW, Howes C, Pattison C, So K, Mariani G, Savage M, Mair S, Ford G, Martin P. Dymond AW, et al. Clin Ther. 2016 Nov;38(11):2447-2458. doi: 10.1016/j.clinthera.2016.09.002. Epub 2016 Oct 15. Clin Ther. 2016. PMID: 27751676 Clinical Trial.

7

Pharmacokinetic Properties of Fostamatinib in Patients With Renal or Hepatic Impairment: Results From 2 Phase I Clinical Studies.

Martin P, Oliver S, Gillen M, Marbury T, Millson D. Martin P, et al. Clin Ther. 2015 Dec 1;37(12):2823-36. doi: 10.1016/j.clinthera.2015.09.016. Epub 2015 Oct 27. Clin Ther. 2015. PMID: 26519231 Clinical Trial.

8

Pharmacokinetic-pharmacodynamic modeling of fostamatinib efficacy on ACR20 to support dose selection in patients with rheumatoid arthritis (RA).

Maringwa J, Kågedal M, Hamrén UW, Martin P, Cox E, Hamrén B. Maringwa J, et al. J Clin Pharmacol. 2015 Mar;55(3):328-35. doi: 10.1002/jcph.406. Epub 2014 Nov 20. J Clin Pharmacol. 2015. PMID: 25280085 Clinical Trial.

9

AZD6244 (ARRY-142886), a potent inhibitor of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase 1/2 kinases: mechanism of action in vivo, pharmacokinetic/pharmacodynamic relationship, and potential for combination in preclinical models.

Davies BR, Logie A, McKay JS, Martin P, Steele S, Jenkins R, Cockerill M, Cartlidge S, Smith PD. Davies BR, et al. Among authors: martin p. Mol Cancer Ther. 2007 Aug;6(8):2209-19. doi: 10.1158/1535-7163.MCT-07-0231. Mol Cancer Ther. 2007. PMID: 17699718

10

Pharmacokinetic drug interactions with vandetanib during coadministration with rifampicin or itraconazole.

Martin P, Oliver S, Robertson J, Kennedy SJ, Read J, Duvauchelle T. Martin P, et al. Drugs R D. 2011;11(1):37-51. doi: 10.2165/11586980-000000000-00000. Drugs R D. 2011. PMID: 21410294 Free PMC article. Clinical Trial.

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