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MyD88, an adapter protein involved in interleukin-1 signaling.
Burns K, Martinon F, Esslinger C, Pahl H, Schneider P, Bodmer JL, Di Marco F, French L, Tschopp J. Burns K, et al. J Biol Chem. 1998 May 15;273(20):12203-9. doi: 10.1074/jbc.273.20.12203. J Biol Chem. 1998. PMID: 9575168
Identification of CARDIAK, a RIP-like kinase that associates with caspase-1.
Thome M, Hofmann K, Burns K, Martinon F, Bodmer JL, Mattmann C, Tschopp J. Thome M, et al. Curr Biol. 1998 Jul 16;8(15):885-8. doi: 10.1016/s0960-9822(07)00352-1. Curr Biol. 1998. PMID: 9705938
Equine herpesvirus-2 E10 gene product, but not its cellular homologue, activates NF-kappaB transcription factor and c-Jun N-terminal kinase.
Thome M, Martinon F, Hofmann K, Rubio V, Steiner V, Schneider P, Mattmann C, Tschopp J. Thome M, et al. J Biol Chem. 1999 Apr 9;274(15):9962-8. doi: 10.1074/jbc.274.15.9962. J Biol Chem. 1999. PMID: 10187771
Apoptosis: Silencing the death receptors.
Tschopp J, Martinon F, Hofmann K. Tschopp J, et al. Curr Biol. 1999 May 20;9(10):R381-4. doi: 10.1016/s0960-9822(99)80233-4. Curr Biol. 1999. PMID: 10339421 Review.
The caspase-8 inhibitor FLIP promotes activation of NF-kappaB and Erk signaling pathways.
Kataoka T, Budd RC, Holler N, Thome M, Martinon F, Irmler M, Burns K, Hahne M, Kennedy N, Kovacsovics M, Tschopp J. Kataoka T, et al. Curr Biol. 2000 Jun 1;10(11):640-8. doi: 10.1016/s0960-9822(00)00512-1. Curr Biol. 2000. PMID: 10837247
Tollip, a new component of the IL-1RI pathway, links IRAK to the IL-1 receptor.
Burns K, Clatworthy J, Martin L, Martinon F, Plumpton C, Maschera B, Lewis A, Ray K, Tschopp J, Volpe F. Burns K, et al. Nat Cell Biol. 2000 Jun;2(6):346-51. doi: 10.1038/35014038. Nat Cell Biol. 2000. PMID: 10854325
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