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Spermidine metabolism regulates leukemia stem and progenitor cell function through KAT7 expression in patient-derived mouse models.
Rondeau V, Berman JM, Ling T, O'Brien C, Culp-Hill R, Reisz JA, Wunderlich M, Chueh Y, Jiménez-Camacho KE, Sexton C, Carter KM, Stillwell C, St-Germain J, Yendi D, Gupta A, Shi M, Bourdine A, Paralkar VR, Jahangiri S, Hope KJ, Tikhonova AN, Arruda A, Minden MD, Raught B, D'Alessandro A, Jones CL. Rondeau V, et al. Among authors: shi m. Sci Transl Med. 2024 Sep 25;16(766):eadn1285. doi: 10.1126/scitranslmed.adn1285. Epub 2024 Sep 25. Sci Transl Med. 2024. PMID: 39321266 Free PMC article.
Glutaredoxin 2 is essential for AML survival through mitochondrial permeability transition pore regulation.
Ling T, O'Brien C, St-Germain J, Rondeau V, Shi M, Berman JM, Cepa AK, Saez Raez P, Wunderlich M, Carter K, Stillwell C, Sexton CR, Culp-Hill R, Reisz JA, Adeel SA, Zeng AGX, Bansal S, Tsao E, Chen HTT, Dick JE, Minden MD, Arruda A, Amaya ML, Tikhonova AN, Hope K, D'Alessandro A, Raught B, Jones CL. Ling T, et al. Among authors: shi m. Blood. 2025 Nov 14:blood.2025028933. doi: 10.1182/blood.2025028933. Online ahead of print. Blood. 2025. PMID: 41237364
CRISPR Screen Identifies HDAC3 as a Novel Radiosensitizing Target in Small Cell Lung Cancer.
Patel UA, Shi MY, Kazan JM, Nixon KCJ, Ran X, Nair SN, Huang O, Song L, Aparnathi MK, He MY, Bakhtiari M, Krishnan R, Hessenow RK, Philip V, Ketela T, Jendrossek V, Hakem R, He HH, Kridel R, Lok BH. Patel UA, et al. Among authors: shi my. Mol Cancer Ther. 2026 Jan 2;25(1):183-195. doi: 10.1158/1535-7163.MCT-24-0861. Mol Cancer Ther. 2026. PMID: 40899441 Free PMC article.