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Purification and characterization of oxidoreductases-catalyzing carbonyl reduction of the tobacco-specific nitrosamine 4-methylnitrosamino-1-(3-pyridyl)-1-butanone (NNK) in human liver cytosol.
Atalla A, Breyer-Pfaff U, Maser E. Atalla A, et al. Among authors: maser e. Xenobiotica. 2000 Aug;30(8):755-69. doi: 10.1080/00498250050119826. Xenobiotica. 2000. PMID: 11037109
The hop-derived compounds xanthohumol, isoxanthohumol and 8-prenylnaringenin are tight-binding inhibitors of human aldo-keto reductases 1B1 and 1B10.
Seliger JM, Misuri L, Maser E, Hintzpeter J. Seliger JM, et al. Among authors: maser e. J Enzyme Inhib Med Chem. 2018 Dec;33(1):607-614. doi: 10.1080/14756366.2018.1437728. J Enzyme Inhib Med Chem. 2018. PMID: 29532688 Free PMC article.
Curcumin is a tight-binding inhibitor of the most efficient human daunorubicin reductase--Carbonyl reductase 1.
Hintzpeter J, Hornung J, Ebert B, Martin HJ, Maser E. Hintzpeter J, et al. Among authors: maser e. Chem Biol Interact. 2015 Jun 5;234:162-8. doi: 10.1016/j.cbi.2014.12.019. Epub 2014 Dec 22. Chem Biol Interact. 2015. PMID: 25541467
Studies on reduction of S-nitrosoglutathione by human carbonyl reductases 1 and 3.
Staab CA, Hartmanová T, El-Hawari Y, Ebert B, Kisiela M, Wsol V, Martin HJ, Maser E. Staab CA, et al. Among authors: maser e. Chem Biol Interact. 2011 May 30;191(1-3):95-103. doi: 10.1016/j.cbi.2011.01.016. Epub 2011 Jan 21. Chem Biol Interact. 2011. PMID: 21256830
The Drosophila carbonyl reductase sniffer is an efficient 4-oxonon-2-enal (4ONE) reductase.
Martin HJ, Ziemba M, Kisiela M, Botella JA, Schneuwly S, Maser E. Martin HJ, et al. Among authors: maser e. Chem Biol Interact. 2011 May 30;191(1-3):48-54. doi: 10.1016/j.cbi.2010.12.006. Epub 2010 Dec 15. Chem Biol Interact. 2011. PMID: 21167142
Reduction of lipid peroxidation products and advanced glycation end-product precursors by cyanobacterial aldo-keto reductase AKR3G1—a founding member of the AKR3G subfamily.
Hintzpeter J, Martin HJ, Maser E. Hintzpeter J, et al. Among authors: maser e. FASEB J. 2015 Jan;29(1):263-73. doi: 10.1096/fj.14-258327. Epub 2014 Nov 5. FASEB J. 2015. PMID: 25376835
Carbonyl reductase sniffer from the model organism daphnia: Cloning, substrate determination and inhibitory sensitivity.
Strehse JS, Protopapas N, Maser E. Strehse JS, et al. Among authors: maser e. Chem Biol Interact. 2019 Jul 1;307:29-36. doi: 10.1016/j.cbi.2019.04.011. Epub 2019 Apr 13. Chem Biol Interact. 2019. PMID: 30991043
Different inhibitory potential of sex hormones on NNK detoxification in vitro: A possible explanation for gender-specific lung cancer risk.
Stapelfeld C, Neumann KT, Maser E. Stapelfeld C, et al. Among authors: maser e. Cancer Lett. 2017 Oct 1;405:120-126. doi: 10.1016/j.canlet.2017.07.016. Epub 2017 Jul 22. Cancer Lett. 2017. PMID: 28743530
Sex hormones reduce NNK detoxification through inhibition of short-chain dehydrogenases/reductases and aldo-keto reductases in vitro.
Stapelfeld C, Maser E. Stapelfeld C, et al. Among authors: maser e. Chem Biol Interact. 2017 Oct 1;276:167-173. doi: 10.1016/j.cbi.2017.02.016. Epub 2017 Feb 28. Chem Biol Interact. 2017. PMID: 28257955
Human DCXR - another 'moonlighting protein' involved in sugar metabolism, carbonyl detoxification, cell adhesion and male fertility?
Ebert B, Kisiela M, Maser E. Ebert B, et al. Among authors: maser e. Biol Rev Camb Philos Soc. 2015 Feb;90(1):254-78. doi: 10.1111/brv.12108. Epub 2014 Apr 10. Biol Rev Camb Philos Soc. 2015. PMID: 24720935 Review.
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