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Novel variants of major drug-metabolising enzyme genes in diverse African populations and their predicted functional effects.
Matimba A, Del-Favero J, Van Broeckhoven C, Masimirembwa C. Matimba A, et al. Among authors: masimirembwa c. Hum Genomics. 2009 Jan;3(2):169-90. doi: 10.1186/1479-7364-3-2-169. Hum Genomics. 2009. PMID: 19164093 Free PMC article.
Cytochrome P450 pharmacogenetics in African populations: implications for public health.
Dandara C, Swart M, Mpeta B, Wonkam A, Masimirembwa C. Dandara C, et al. Among authors: masimirembwa c. Expert Opin Drug Metab Toxicol. 2014 Jun;10(6):769-85. doi: 10.1517/17425255.2014.894020. Epub 2014 Mar 3. Expert Opin Drug Metab Toxicol. 2014. PMID: 24588448 Review.
An African-specific profile of pharmacogene variants for rosuvastatin plasma variability: limited role for SLCO1B1 c.521T>C and ABCG2 c.421A>C.
Soko ND, Chimusa E, Masimirembwa C, Dandara C. Soko ND, et al. Among authors: masimirembwa c. Pharmacogenomics J. 2019 Jun;19(3):240-248. doi: 10.1038/s41397-018-0035-3. Epub 2018 Aug 13. Pharmacogenomics J. 2019. PMID: 30100615
A cost effective RFLP method to genotype Solute carrier organic anion 1B1 (SLCO1B1) c.1929A>C (p.Leu643Phe, rs34671512); a variant with potential effect on rosuvastatin pharmacokinetics.
Soko ND, Masimirembwa C, Dandara C. Soko ND, et al. Among authors: masimirembwa c. BMC Res Notes. 2018 Jun 14;11(1):384. doi: 10.1186/s13104-018-3469-4. BMC Res Notes. 2018. PMID: 29898760 Free PMC article.
Rosuvastatin pharmacogenetics in African populations.
Soko ND, Masimirembwa C, Dandara C. Soko ND, et al. Among authors: masimirembwa c. Pharmacogenomics. 2018 Dec;19(18):1373-1375. doi: 10.2217/pgs-2018-0168. Epub 2018 Nov 6. Pharmacogenomics. 2018. PMID: 30398065 Free article. No abstract available.
African Genetic Diversity: Implications for Cytochrome P450-mediated Drug Metabolism and Drug Development.
Rajman I, Knapp L, Morgan T, Masimirembwa C. Rajman I, et al. Among authors: masimirembwa c. EBioMedicine. 2017 Mar;17:67-74. doi: 10.1016/j.ebiom.2017.02.017. Epub 2017 Feb 20. EBioMedicine. 2017. PMID: 28237373 Free PMC article.
Prediction of sites under adaptive evolution in cytochrome P450 sequences and their relationship to substrate recognition sites.
Zawaira A, Matimba A, Masimirembwa C. Zawaira A, et al. Among authors: masimirembwa c. Pharmacogenet Genomics. 2008 Jun;18(6):467-76. doi: 10.1097/FPC.0b013e3282f9b68e. Pharmacogenet Genomics. 2008. PMID: 18496126
Physicochemical and drug metabolism characterization of a series of 4-aminoquinoline-3-hydroxypyridin-4-one hybrid molecules with antimalarial activity.
Thelingwani R, Bonn B, Chibale K, Masimirembwa C. Thelingwani R, et al. Among authors: masimirembwa c. Expert Opin Drug Metab Toxicol. 2014 Oct;10(10):1313-24. doi: 10.1517/17425255.2014.954547. Expert Opin Drug Metab Toxicol. 2014. PMID: 25219629
Pharmacogenomics of Rosuvastatin: A Glocal (Global+Local) African Perspective and Expert Review on a Statin Drug.
Soko ND, Masimirembwa C, Dandara C. Soko ND, et al. Among authors: masimirembwa c. OMICS. 2016 Sep;20(9):498-509. doi: 10.1089/omi.2016.0114. OMICS. 2016. PMID: 27631189 Review.
Genetic variants of drug metabolizing enzymes and drug transporter (ABCB1) as possible biomarkers for adverse drug reactions in an HIV/AIDS cohort in Zimbabwe.
Dhoro M, Ngara B, Kadzirange G, Nhachi C, Masimirembwa C. Dhoro M, et al. Among authors: masimirembwa c. Curr HIV Res. 2013 Sep;11(6):481-90. doi: 10.2174/1570162x113119990048. Curr HIV Res. 2013. PMID: 24517233
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