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Proteolytic cleavage of granulocyte colony-stimulating factor and its receptor by neutrophil elastase induces growth inhibition and decreased cell surface expression of the granulocyte colony-stimulating factor receptor.
Am J Hematol. 2003 Nov;74(3):149-55. doi: 10.1002/ajh.10434.
Am J Hematol. 2003.
PMID: 14587040
Free article.
Novel mechanism of G-CSF refractoriness in patients with severe congenital neutropenia.
Druhan LJ, Ai J, Massullo P, Kindwall-Keller T, Ranalli MA, Avalos BR.
Druhan LJ, et al.
Blood. 2005 Jan 15;105(2):584-91. doi: 10.1182/blood-2004-07-2613. Epub 2004 Sep 7.
Blood. 2005.
PMID: 15353486
Free article.
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Aberrant subcellular targeting of the G185R neutrophil elastase mutant associated with severe congenital neutropenia induces premature apoptosis of differentiating promyelocytes.
Massullo P, Druhan LJ, Bunnell BA, Hunter MG, Robinson JM, Marsh CB, Avalos BR.
Massullo P, et al.
Blood. 2005 May 1;105(9):3397-404. doi: 10.1182/blood-2004-07-2618. Epub 2005 Jan 18.
Blood. 2005.
PMID: 15657182
Free PMC article.
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Role of the proteasome in modulating native G-CSFR expression.
Kindwall-Keller TL, Druhan LJ, Ai J, Hunter MG, Massullo P, Loveland M, Avalos BR.
Kindwall-Keller TL, et al.
Cytokine. 2008 Aug;43(2):114-23. doi: 10.1016/j.cyto.2008.04.015. Epub 2008 Jun 12.
Cytokine. 2008.
PMID: 18554923
Free PMC article.
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Neutrophil elastase downmodulates native G-CSFR expression and granulocyte-macrophage colony formation.
Piper MG, Massullo PR, Loveland M, Druhan LJ, Kindwall-Keller TL, Ai J, Copelan A, Avalos BR.
Piper MG, et al. Among authors: massullo pr.
J Inflamm (Lond). 2010 Jan 21;7(1):5. doi: 10.1186/1476-9255-7-5.
J Inflamm (Lond). 2010.
PMID: 20205821
Free PMC article.
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TRPM channels, calcium and redox sensors during innate immune responses.
Massullo P, Sumoza-Toledo A, Bhagat H, Partida-Sánchez S.
Massullo P, et al.
Semin Cell Dev Biol. 2006 Dec;17(6):654-66. doi: 10.1016/j.semcdb.2006.11.006. Epub 2006 Nov 21.
Semin Cell Dev Biol. 2006.
PMID: 17178241
Review.
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