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Cross-disciplinary research stirs new challenges into the study of the structure, function and systems biology of complement.

Mastellos D, Lambris JD. Mastellos D, et al. Adv Exp Med Biol. 2006;586:1-16. doi: 10.1007/0-387-34134-X_1. Adv Exp Med Biol. 2006. PMID: 16893061 Review. No abstract available.

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Phylogenetic aspects of the complement system.

Zarkadis IK, Mastellos D, Lambris JD. Zarkadis IK, et al. Among authors: mastellos d. Dev Comp Immunol. 2001 Oct-Dec;25(8-9):745-62. doi: 10.1016/s0145-305x(01)00034-9. Dev Comp Immunol. 2001. PMID: 11602194 Review.

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From atoms to systems: a cross-disciplinary approach to complement-mediated functions.

Mastellos D, Morikis D, Strey C, Holland MC, Lambris JD. Mastellos D, et al. Mol Immunol. 2004 Jun;41(2-3):153-64. doi: 10.1016/j.molimm.2004.03.016. Mol Immunol. 2004. PMID: 15159061 Review.

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Targeting innate immune pathways in cancer immunotherapy: state of the art.

Mastellos DC. Mastellos DC. J BUON. 2009 Sep;14 Suppl 1:S123-30. J BUON. 2009. PMID: 19785054 Review.

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Complement-triggered pathways orchestrate regenerative responses throughout phylogenesis.

Mastellos DC, Deangelis RA, Lambris JD. Mastellos DC, et al. Semin Immunol. 2013 Feb;25(1):29-38. doi: 10.1016/j.smim.2013.04.002. Epub 2013 May 17. Semin Immunol. 2013. PMID: 23684626 Free PMC article. Review.

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Complement emerges as a masterful regulator of CNS homeostasis, neural synaptic plasticity and cognitive function.

Mastellos DC. Mastellos DC. Exp Neurol. 2014 Nov;261:469-74. doi: 10.1016/j.expneurol.2014.06.019. Epub 2014 Jun 26. Exp Neurol. 2014. PMID: 24975369

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Complement in paroxysmal nocturnal hemoglobinuria: exploiting our current knowledge to improve the treatment landscape.

Mastellos DC, Ricklin D, Yancopoulou D, Risitano A, Lambris JD. Mastellos DC, et al. Expert Rev Hematol. 2014 Oct;7(5):583-98. doi: 10.1586/17474086.2014.953926. Epub 2014 Sep 2. Expert Rev Hematol. 2014. PMID: 25213458 Free PMC article. Review.

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Complement therapeutics in inflammatory diseases: promising drug candidates for C3-targeted intervention.

Mastellos DC, Ricklin D, Hajishengallis E, Hajishengallis G, Lambris JD. Mastellos DC, et al. Mol Oral Microbiol. 2016 Feb;31(1):3-17. doi: 10.1111/omi.12129. Epub 2015 Oct 7. Mol Oral Microbiol. 2016. PMID: 26332138 Free PMC article. Review.

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Applying complement therapeutics to rare diseases.

Reis ES, Mastellos DC, Yancopoulou D, Risitano AM, Ricklin D, Lambris JD. Reis ES, et al. Among authors: mastellos dc. Clin Immunol. 2015 Dec;161(2):225-40. doi: 10.1016/j.clim.2015.08.009. Epub 2015 Sep 1. Clin Immunol. 2015. PMID: 26341313 Free PMC article. Review.

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Complement component C3 - The "Swiss Army Knife" of innate immunity and host defense.

Ricklin D, Reis ES, Mastellos DC, Gros P, Lambris JD. Ricklin D, et al. Among authors: mastellos dc. Immunol Rev. 2016 Nov;274(1):33-58. doi: 10.1111/imr.12500. Immunol Rev. 2016. PMID: 27782325 Free PMC article. Review.

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