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Protease-activated receptor 2 sensitizes the transient receptor potential vanilloid 4 ion channel to cause mechanical hyperalgesia in mice.
Grant AD, Cottrell GS, Amadesi S, Trevisani M, Nicoletti P, Materazzi S, Altier C, Cenac N, Zamponi GW, Bautista-Cruz F, Lopez CB, Joseph EK, Levine JD, Liedtke W, Vanner S, Vergnolle N, Geppetti P, Bunnett NW. Grant AD, et al. Among authors: materazzi s. J Physiol. 2007 Feb 1;578(Pt 3):715-33. doi: 10.1113/jphysiol.2006.121111. Epub 2006 Nov 23. J Physiol. 2007. PMID: 17124270 Free PMC article.
4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1.
Trevisani M, Siemens J, Materazzi S, Bautista DM, Nassini R, Campi B, Imamachi N, Andrè E, Patacchini R, Cottrell GS, Gatti R, Basbaum AI, Bunnett NW, Julius D, Geppetti P. Trevisani M, et al. Among authors: materazzi s. Proc Natl Acad Sci U S A. 2007 Aug 14;104(33):13519-24. doi: 10.1073/pnas.0705923104. Epub 2007 Aug 7. Proc Natl Acad Sci U S A. 2007. PMID: 17684094 Free PMC article.
The concept of neurogenic inflammation.
Geppetti P, Nassini R, Materazzi S, Benemei S. Geppetti P, et al. Among authors: materazzi s. BJU Int. 2008 Mar;101 Suppl 3:2-6. doi: 10.1111/j.1464-410X.2008.07493.x. BJU Int. 2008. PMID: 18307678 Review.
Cigarette smoke-induced neurogenic inflammation is mediated by alpha,beta-unsaturated aldehydes and the TRPA1 receptor in rodents.
Andrè E, Campi B, Materazzi S, Trevisani M, Amadesi S, Massi D, Creminon C, Vaksman N, Nassini R, Civelli M, Baraldi PG, Poole DP, Bunnett NW, Geppetti P, Patacchini R. Andrè E, et al. Among authors: materazzi s. J Clin Invest. 2008 Jul;118(7):2574-82. doi: 10.1172/JCI34886. J Clin Invest. 2008. PMID: 18568077 Free PMC article.
Cough: The Emerging Role of the TRPA1 Channel.
Geppetti P, Patacchini R, Nassini R, Materazzi S. Geppetti P, et al. Among authors: materazzi s. Lung. 2010 Jan;188 Suppl 1:S63-8. doi: 10.1007/s00408-009-9201-3. Epub 2009 Nov 30. Lung. 2010. PMID: 20091046 Review.
Migraine models.
Benemei S, De Cesaris F, Nicoletti P, Materazzi S, Nassini R, Geppetti P. Benemei S, et al. Among authors: materazzi s. Methods Mol Biol. 2010;617:105-14. doi: 10.1007/978-1-60327-323-7_9. Methods Mol Biol. 2010. PMID: 20336417
122 results