Mathôt RA - Search Results

1

A population analysis of the pharmacokinetics of Cremophor EL using nonlinear mixed-effect modelling.

van den Bongard HJ, Mathôt RA, van Tellingen O, Schellens JH, Beijnen JH. van den Bongard HJ, et al. Among authors: mathot ra. Cancer Chemother Pharmacol. 2002 Jul;50(1):16-24. doi: 10.1007/s00280-002-0459-x. Epub 2002 May 1. Cancer Chemother Pharmacol. 2002. PMID: 12111107

2

Modelling of the pharmacodynamic interaction of an A1 adenosine receptor agonist and antagonist in vivo: N6-cyclopentyladenosine and 8-cyclopentyltheophylline.

Appel S, Mathôt RA, Langemeijer MW, IJzerman AP, Danhof M. Appel S, et al. Among authors: mathot ra. Br J Pharmacol. 1995 Aug;115(7):1253-9. doi: 10.1111/j.1476-5381.1995.tb15033.x. Br J Pharmacol. 1995. PMID: 7582553 Free PMC article.

3

Evaluation of the autoinduction of ifosfamide metabolism by a population pharmacokinetic approach using NONMEM.

Kerbusch T, Huitema AD, Ouwerkerk J, Keizer HJ, Mathôt RA, Schellens JH, Beijnen JH. Kerbusch T, et al. Among authors: mathot ra. Br J Clin Pharmacol. 2000 Jun;49(6):555-61. doi: 10.1046/j.1365-2125.2000.00217.x. Br J Clin Pharmacol. 2000. PMID: 10848719 Free PMC article. Clinical Trial.

4

Validation of techniques for the prediction of carboplatin exposure: application of Bayesian methods.

Huitema AD, Mathôt RA, Tibben MM, Schellens JH, Rodenhuis S, Beijnen JH. Huitema AD, et al. Among authors: mathot ra. Clin Pharmacol Ther. 2000 Jun;67(6):621-30. doi: 10.1067/mcp.2000.106827. Clin Pharmacol Ther. 2000. PMID: 10872644

5

The clinical pharmacology of alkylating agents in high-dose chemotherapy.

Huitema AD, Smits KD, Mathôt RA, Schellens JH, Rodenhuis S, Beijnen JH. Huitema AD, et al. Among authors: mathot ra. Anticancer Drugs. 2000 Aug;11(7):515-33. doi: 10.1097/00001813-200008000-00002. Anticancer Drugs. 2000. PMID: 11036954 Review.

6

Pharmacokinetically guided administration of chemotherapeutic agents.

van den Bongard HJ, Mathôt RA, Beijnen JH, Schellens JH. van den Bongard HJ, et al. Among authors: mathot ra. Clin Pharmacokinet. 2000 Nov;39(5):345-67. doi: 10.2165/00003088-200039050-00004. Clin Pharmacokinet. 2000. PMID: 11108434 Review.

7

Population pharmacokinetics of thioTEPA and its active metabolite TEPA in patients undergoing high-dose chemotherapy.

Huitema AD, Mathôt RA, Tibben MM, Schellens JH, Rodenhuis S, Beijnen JH. Huitema AD, et al. Among authors: mathot ra. Br J Clin Pharmacol. 2001 Jan;51(1):61-70. doi: 10.1046/j.1365-2125.2001.01301.x. Br J Clin Pharmacol. 2001. PMID: 11167666 Free PMC article.

8

Influence of dose and infusion duration on pharmacokinetics of ifosfamide and metabolites.

Kerbusch T, Mathôt RA, Keizer HJ, Kaijser GP, Schellens JH, Beijnen JH. Kerbusch T, et al. Among authors: mathot ra. Drug Metab Dispos. 2001 Jul;29(7):967-75. Drug Metab Dispos. 2001. PMID: 11408362

9

The effect of fluconazole on ritonavir and saquinavir pharmacokinetics in HIV-1-infected individuals.

Koks CH, Crommentuyn KM, Hoetelmans RM, Burger DM, Koopmans PP, Mathôt RA, Mulder JW, Meenhorst PL, Beijnen JH. Koks CH, et al. Among authors: mathot ra. Br J Clin Pharmacol. 2001 Jun;51(6):631-5. doi: 10.1046/j.0306-5251.2001.01409.x. Br J Clin Pharmacol. 2001. PMID: 11422025 Free PMC article. Clinical Trial.

10

A mechanism-based pharmacokinetic model for the cytochrome P450 drug-drug interaction between cyclophosphamide and thioTEPA and the autoinduction of cyclophosphamide.

Huitema AD, Mathôt RA, Tibben MM, Rodenhuis S, Beijnen JH. Huitema AD, et al. Among authors: mathot ra. J Pharmacokinet Pharmacodyn. 2001 Jun;28(3):211-30. doi: 10.1023/a:1011543508731. J Pharmacokinet Pharmacodyn. 2001. PMID: 11468938

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