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QPatch: the past, present and future of automated patch clamp.
Mathes C. Mathes C. Expert Opin Ther Targets. 2006 Apr;10(2):319-27. doi: 10.1517/14728222.10.2.319. Expert Opin Ther Targets. 2006. PMID: 16548779 Review.
Characterization of compounds on nicotinic acetylcholine receptor alpha7 channels using higher throughput electrophysiology.
Friis S, Mathes C, Sunesen M, Bowlby MR, Dunlop J. Friis S, et al. J Neurosci Methods. 2009 Feb 15;177(1):142-8. doi: 10.1016/j.jneumeth.2008.10.007. Epub 2008 Oct 19. J Neurosci Methods. 2009. PMID: 19000713
Identifying modulators of hERG channel activity using the PatchXpress planar patch clamp.
Dubin AE, Nasser N, Rohrbacher J, Hermans AN, Marrannes R, Grantham C, Van Rossem K, Cik M, Chaplan SR, Gallacher D, Xu J, Guia A, Byrne NG, Mathes C. Dubin AE, et al. J Biomol Screen. 2005 Mar;10(2):168-81. doi: 10.1177/1087057104272295. J Biomol Screen. 2005. PMID: 15799960
QPatch: the missing link between HTS and ion channel drug discovery.
Mathes C, Friis S, Finley M, Liu Y. Mathes C, et al. Comb Chem High Throughput Screen. 2009 Jan;12(1):78-95. doi: 10.2174/138620709787047948. Comb Chem High Throughput Screen. 2009. PMID: 19149494 Review.
Automated patch-clamp technique: increased throughput in functional characterization and in pharmacological screening of small-conductance Ca2+ release-activated Ca2+ channels.
Schrøder RL, Friis S, Sunesen M, Mathes C, Willumsen NJ. Schrøder RL, et al. J Biomol Screen. 2008 Aug;13(7):638-47. doi: 10.1177/1087057108320274. Epub 2008 Jul 3. J Biomol Screen. 2008. PMID: 18599880
Ion channels in drug discovery and development.
Mathes C. Mathes C. Drug Discov Today. 2003 Nov 15;8(22):1022-4. doi: 10.1016/s1359-6446(03)02875-7. Drug Discov Today. 2003. PMID: 14690632 No abstract available.
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