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Alternative approaches for identifying acute systemic toxicity: Moving from research to regulatory testing.
Hamm J, Sullivan K, Clippinger AJ, Strickland J, Bell S, Bhhatarai B, Blaauboer B, Casey W, Dorman D, Forsby A, Garcia-Reyero N, Gehen S, Graepel R, Hotchkiss J, Lowit A, Matheson J, Reaves E, Scarano L, Sprankle C, Tunkel J, Wilson D, Xia M, Zhu H, Allen D. Hamm J, et al. Among authors: matheson j. Toxicol In Vitro. 2017 Jun;41:245-259. doi: 10.1016/j.tiv.2017.01.004. Epub 2017 Jan 6. Toxicol In Vitro. 2017. PMID: 28069485 Free PMC article. Review.
Adverse outcome pathways: From research to regulation scientific workshop report.
Kleinstreuer NC, Sullivan K, Allen D, Edwards S, Mendrick DL, Embry M, Matheson J, Rowlands JC, Munn S, Maull E, Casey W. Kleinstreuer NC, et al. Among authors: matheson j. Regul Toxicol Pharmacol. 2016 Apr;76:39-50. doi: 10.1016/j.yrtph.2016.01.007. Epub 2016 Jan 14. Regul Toxicol Pharmacol. 2016. PMID: 26774756 Free PMC article.
Integrated decision strategies for skin sensitization hazard.
Strickland J, Zang Q, Kleinstreuer N, Paris M, Lehmann DM, Choksi N, Matheson J, Jacobs A, Lowit A, Allen D, Casey W. Strickland J, et al. Among authors: matheson j. J Appl Toxicol. 2016 Sep;36(9):1150-62. doi: 10.1002/jat.3281. Epub 2016 Feb 6. J Appl Toxicol. 2016. PMID: 26851134 Free PMC article.
Multivariate models for prediction of human skin sensitization hazard.
Strickland J, Zang Q, Paris M, Lehmann DM, Allen D, Choksi N, Matheson J, Jacobs A, Casey W, Kleinstreuer N. Strickland J, et al. Among authors: matheson j. J Appl Toxicol. 2017 Mar;37(3):347-360. doi: 10.1002/jat.3366. Epub 2016 Aug 2. J Appl Toxicol. 2017. PMID: 27480324 Free PMC article.
Prediction of skin sensitization potency using machine learning approaches.
Zang Q, Paris M, Lehmann DM, Bell S, Kleinstreuer N, Allen D, Matheson J, Jacobs A, Casey W, Strickland J. Zang Q, et al. Among authors: matheson j. J Appl Toxicol. 2017 Jul;37(7):792-805. doi: 10.1002/jat.3424. Epub 2017 Jan 10. J Appl Toxicol. 2017. PMID: 28074598 Free PMC article.
Integrated decision strategies for skin sensitization hazard.
Strickland J, Zang Q, Kleinstreuer N, Paris M, Lehmann DM, Choksi N, Matheson J, Jacobs A, Lowit A, Allen D, Casey W. Strickland J, et al. Among authors: matheson j. J Appl Toxicol. 2018 Mar;38(3):432. doi: 10.1002/jat.3572. Epub 2017 Nov 29. J Appl Toxicol. 2018. PMID: 29363186 No abstract available.
Status of acute systemic toxicity testing requirements and data uses by U.S. regulatory agencies.
Strickland J, Clippinger AJ, Brown J, Allen D, Jacobs A, Matheson J, Lowit A, Reinke EN, Johnson MS, Quinn MJ Jr, Mattie D, Fitzpatrick SC, Ahir S, Kleinstreuer N, Casey W. Strickland J, et al. Among authors: matheson j. Regul Toxicol Pharmacol. 2018 Apr;94:183-196. doi: 10.1016/j.yrtph.2018.01.022. Epub 2018 Feb 3. Regul Toxicol Pharmacol. 2018. PMID: 29408321 Free PMC article. Review.
Skin sensitization testing needs and data uses by US regulatory and research agencies.
Strickland J, Daniel AB, Allen D, Aguila C, Ahir S, Bancos S, Craig E, Germolec D, Ghosh C, Hudson NL, Jacobs A, Lehmann DM, Matheson J, Reinke EN, Sadrieh N, Vukmanovic S, Kleinstreuer N. Strickland J, et al. Among authors: matheson j. Arch Toxicol. 2019 Feb;93(2):273-291. doi: 10.1007/s00204-018-2341-6. Epub 2018 Oct 30. Arch Toxicol. 2019. PMID: 30377734 Free PMC article. Review.
United States regulatory requirements for skin and eye irritation testing.
Choksi NY, Truax J, Layton A, Matheson J, Mattie D, Varney T, Tao J, Yozzo K, McDougal AJ, Merrill J, Lowther D, Barroso J, Linke B, Casey W, Allen D. Choksi NY, et al. Among authors: matheson j. Cutan Ocul Toxicol. 2019 Jun;38(2):141-155. doi: 10.1080/15569527.2018.1540494. Epub 2018 Dec 26. Cutan Ocul Toxicol. 2019. PMID: 30418044 Free PMC article. Review.
310 results