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Perhexiline activates KLF14 and reduces atherosclerosis by modulating ApoA-I production.
Guo Y, Fan Y, Zhang J, Lomberk GA, Zhou Z, Sun L, Mathison AJ, Garcia-Barrio MT, Zhang J, Zeng L, Li L, Pennathur S, Willer CJ, Rader DJ, Urrutia R, Chen YE. Guo Y, et al. Among authors: mathison aj. J Clin Invest. 2015 Oct 1;125(10):3819-30. doi: 10.1172/JCI79048. Epub 2015 Sep 14. J Clin Invest. 2015. PMID: 26368306 Free PMC article.
Detailed structural-functional analysis of the Krüppel-like factor 16 (KLF16) transcription factor reveals novel mechanisms for silencing Sp/KLF sites involved in metabolism and endocrinology.
Daftary GS, Lomberk GA, Buttar NS, Allen TW, Grzenda A, Zhang J, Zheng Y, Mathison AJ, Gada RP, Calvo E, Iovanna JL, Billadeau DD, Prendergast FG, Urrutia R. Daftary GS, et al. Among authors: mathison aj. J Biol Chem. 2012 Mar 2;287(10):7010-25. doi: 10.1074/jbc.M111.266007. Epub 2011 Dec 27. J Biol Chem. 2012. PMID: 22203677 Free PMC article.
Sequence-specific recruitment of heterochromatin protein 1 via interaction with Krüppel-like factor 11, a human transcription factor involved in tumor suppression and metabolic diseases.
Lomberk G, Mathison AJ, Grzenda A, Seo S, DeMars CJ, Rizvi S, Bonilla-Velez J, Calvo E, Fernandez-Zapico ME, Iovanna J, Buttar NS, Urrutia R. Lomberk G, et al. Among authors: mathison aj. J Biol Chem. 2012 Apr 13;287(16):13026-39. doi: 10.1074/jbc.M112.342634. Epub 2012 Feb 8. J Biol Chem. 2012. PMID: 22318730 Free PMC article.
Krüppel-like factor 11 differentially couples to histone acetyltransferase and histone methyltransferase chromatin remodeling pathways to transcriptionally regulate dopamine D2 receptor in neuronal cells.
Seo S, Lomberk G, Mathison A, Buttar N, Podratz J, Calvo E, Iovanna J, Brimijoin S, Windebank A, Urrutia R. Seo S, et al. J Biol Chem. 2012 Apr 13;287(16):12723-35. doi: 10.1074/jbc.M112.351395. Epub 2012 Feb 28. J Biol Chem. 2012. PMID: 22375010 Free PMC article.
Krüppel-like factor 11 regulates the expression of metabolic genes via an evolutionarily conserved protein interaction domain functionally disrupted in maturity onset diabetes of the young.
Lomberk G, Grzenda A, Mathison A, Escande C, Zhang JS, Calvo E, Miller LJ, Iovanna J, Chini EN, Fernandez-Zapico ME, Urrutia R. Lomberk G, et al. J Biol Chem. 2013 Jun 14;288(24):17745-58. doi: 10.1074/jbc.M112.434670. Epub 2013 Apr 15. J Biol Chem. 2013. PMID: 23589285 Free PMC article.
58 results