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473 results

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Page 1
Obeticholic acid for the treatment of non-alcoholic steatohepatitis: interim analysis from a multicentre, randomised, placebo-controlled phase 3 trial.
Younossi ZM, Ratziu V, Loomba R, Rinella M, Anstee QM, Goodman Z, Bedossa P, Geier A, Beckebaum S, Newsome PN, Sheridan D, Sheikh MY, Trotter J, Knapple W, Lawitz E, Abdelmalek MF, Kowdley KV, Montano-Loza AJ, Boursier J, Mathurin P, Bugianesi E, Mazzella G, Olveira A, Cortez-Pinto H, Graupera I, Orr D, Gluud LL, Dufour JF, Shapiro D, Campagna J, Zaru L, MacConell L, Shringarpure R, Harrison S, Sanyal AJ; REGENERATE Study Investigators. Younossi ZM, et al. Among authors: mathurin p. Lancet. 2019 Dec 14;394(10215):2184-2196. doi: 10.1016/S0140-6736(19)33041-7. Epub 2019 Dec 5. Lancet. 2019. PMID: 31813633 Free article. Clinical Trial.
Neo-Adjuvant Use of Sorafenib for Hepatocellular Carcinoma Awaiting Liver Transplantation.
Minoux K, Lassailly G, Ningarhari M, Lubret H, El Amrani M, Canva V, Truant S, Mathurin P, Louvet A, Lebuffe G, Goria O, Nguyen-Khac E, Boleslawski E, Dharancy S. Minoux K, et al. Among authors: mathurin p. Transpl Int. 2022 Nov 9;35:10569. doi: 10.3389/ti.2022.10569. eCollection 2022. Transpl Int. 2022. PMID: 36438781 Free PMC article.
Results from a new efficacy and safety analysis of the REGENERATE trial of obeticholic acid for treatment of pre-cirrhotic fibrosis due to non-alcoholic steatohepatitis.
Sanyal AJ, Ratziu V, Loomba R, Anstee QM, Kowdley KV, Rinella ME, Sheikh MY, Trotter JF, Knapple W, Lawitz EJ, Abdelmalek MF, Newsome PN, Boursier J, Mathurin P, Dufour JF, Berrey MM, Shiff SJ, Sawhney S, Capozza T, Leyva R, Harrison SA, Younossi ZM. Sanyal AJ, et al. Among authors: mathurin p. J Hepatol. 2023 Nov;79(5):1110-1120. doi: 10.1016/j.jhep.2023.07.014. Epub 2023 Jul 28. J Hepatol. 2023. PMID: 37517454 Free article. Clinical Trial.
Meta-analysis: Prevalence and impact of alcohol abstinence in alcohol-associated cirrhosis.
Lim WH, Tay P, Ng CH, Tan DJH, Ong C, Koh JH, Teng M, Chee D, Wong ZY, Kawaguchi T, Takahashi H, Muthiah M, Tan EXX, Wijarnpreecha K, Lee GH, Noureddin M, Lee BP, Mathurin P, Loomba R, Huang DQ. Lim WH, et al. Among authors: mathurin p. Aliment Pharmacol Ther. 2024 Mar;59(6):730-741. doi: 10.1111/apt.17888. Epub 2024 Feb 1. Aliment Pharmacol Ther. 2024. PMID: 38303565 Free PMC article. Review.
Implementing sustainable liver health in Europe: a second EASL-Lancet Commission.
Karlsen TH, Hutchinson SJ, Zelber-Sagi S, Carrieri P, Negro F, Lim AG, Cecchini M, Dirac MA, Murray F, Engebretsen E, Duffell E, Schomerus G, Voigt K, Brandtzaeg PB, Lerouge A, Kanavos P, Pani L, Razavi-Shearer D, Eshete MT, Vuik S, Leonhard A, McNaughton AL, Yumuk V, Ivancovsky-Wajcman D, Letourneau ID, Hickman M, Han H, Kautz A, Fabrellas N, Spann AL, Berg T, Ratziu V, Gheorghe LS, Mathurin P, Vickerman P, Shawcross DL, Paradis C, Razavi H, Naveira MCM, Buti M, Ginès P, Newsome PN, Berzigotti A, Guha N, Rutter H, Krag A, Burra P, Manns MP. Karlsen TH, et al. Among authors: mathurin p. Lancet. 2026 May 9;407(10541):1825-1890. doi: 10.1016/S0140-6736(26)00138-8. Epub 2026 Apr 29. Lancet. 2026. PMID: 42068985 Review. No abstract available.
Hepatocyte dedifferentiation profiling in alcohol-related liver disease identifies CXCR4 as a driver of cell reprogramming.
Aguilar-Bravo B, Ariño S, Blaya D, Pose E, Martinez García de la Torre RA, Latasa MU, Martínez-Sánchez C, Zanatto L, Sererols-Viñas L, Cantallops-Vilà P, Affo S, Coll M, Thillen X, Dubuquoy L, Avila MA, Argemi J, Paz AL, Nevzorova YA, Cubero FJ, Bataller R, Lozano JJ, Ginès P, Mathurin P, Sancho-Bru P. Aguilar-Bravo B, et al. Among authors: mathurin p. J Hepatol. 2023 Sep;79(3):728-740. doi: 10.1016/j.jhep.2023.04.013. Epub 2023 Apr 23. J Hepatol. 2023. PMID: 37088308 Free PMC article.
TACE and conformal radiotherapy vs. TACE alone for hepatocellular carcinoma: A randomised controlled trial.
Féray C, Campion L, Mathurin P, Archambreaud I, Mirabel X, Bronowicki JP, Rio E, Perret C, Mineur L, Oberti F, Touchefeu Y, Gournay J, Regnault H, Edeline J, Rode A, Hillion P, Blanc JF, Khac EN, Azoulay D, Luciani A, Preglisasco AG, Faurel-Paul E, Auble H, Mornex F, Merle P. Féray C, et al. Among authors: mathurin p. JHEP Rep. 2023 Jan 29;5(4):100689. doi: 10.1016/j.jhepr.2023.100689. eCollection 2023 Apr. JHEP Rep. 2023. PMID: 36937990 Free PMC article.
Data-driven cluster analysis identifies distinct types of metabolic dysfunction-associated steatotic liver disease.
Raverdy V, Tavaglione F, Chatelain E, Lassailly G, De Vincentis A, Vespasiani-Gentilucci U, Qadri SF, Caiazzo R, Verkindt H, Saponaro C, Kerr-Conte J, Baud G, Marciniak C, Chetboun M, Oukhouya-Daoud N, Blanck S, Vandel J, Olsson L, Chakaroun R, Gnemmi V, Leteurtre E, Lefebvre P, Haas JT, Yki-Järvinen H, Francque S, Staels B, Le Roux CW, Tremaroli V, Mathurin P, Marot G, Romeo S, Pattou F. Raverdy V, et al. Among authors: mathurin p. Nat Med. 2024 Dec;30(12):3624-3633. doi: 10.1038/s41591-024-03283-1. Epub 2024 Dec 9. Nat Med. 2024. PMID: 39653777 Free PMC article.
Targeted inhibition of pathobiont virulence factor mitigates alcohol-associated liver disease.
Yang Y, Duan Y, Lang S, Fondevila MF, Schöler D, Harberts A, Cabré N, Chen S, Shao Y, Vervier K, Miyamoto Y, Zhang X, Chu H, Yang L, Tan C, Eckmann L, Bosques-Padilla F, Verna EC, Abraldes JG, Brown RS Jr, Vargas V, Altamirano J, Caballería J, Shawcross DL, Louvet A, Lucey MR, Mathurin P, Garcia-Tsao G, Bataller R, Stärkel P, Lawley TD, Schnabl B. Yang Y, et al. Among authors: mathurin p. Cell Host Microbe. 2025 Jun 11;33(6):957-972.e6. doi: 10.1016/j.chom.2025.05.003. Epub 2025 May 28. Cell Host Microbe. 2025. PMID: 40441146 Free PMC article.
Author Correction: Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis.
Argemi J, Latasa MU, Atkinson SR, Blokhin IO, Massey V, Gue JP, Cabezas J, Lozano JJ, Van Booven D, Bell A, Cao S, Vernetti LA, Arab JP, Ventura-Cots M, Edmunds LR, Fondevila C, Stärkel P, Dubuquoy L, Louvet A, Odena G, Gomez JL, Aragon T, Altamirano J, Caballeria J, Jurczak MJ, Taylor DL, Berasain C, Wahlestedt C, Monga SP, Morgan MY, Sancho-Bru P, Mathurin P, Furuya S, Lackner C, Rusyn I, Shah VH, Thursz MR, Mann J, Avila MA, Bataller R. Argemi J, et al. Among authors: mathurin p. Nat Commun. 2023 Feb 10;14(1):757. doi: 10.1038/s41467-023-36548-3. Nat Commun. 2023. PMID: 36765087 Free PMC article. No abstract available.
473 results