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Raised plasma soluble Fas and Fas-ligand in alcoholic liver disease.
Taïeb J, Mathurin P, Poynard T, Gougerot-Pocidalo MA, Chollet-Martin S. Taïeb J, et al. Among authors: mathurin p. Lancet. 1998 Jun 27;351(9120):1930-1. doi: 10.1016/S0140-6736(05)78614-1. Lancet. 1998. PMID: 9654266 No abstract available.
Clinical outcomes in patients with chronic hepatitis C after direct-acting antiviral treatment: a prospective cohort study.
Carrat F, Fontaine H, Dorival C, Simony M, Diallo A, Hezode C, De Ledinghen V, Larrey D, Haour G, Bronowicki JP, Zoulim F, Asselah T, Marcellin P, Thabut D, Leroy V, Tran A, Habersetzer F, Samuel D, Guyader D, Chazouilleres O, Mathurin P, Metivier S, Alric L, Riachi G, Gournay J, Abergel A, Cales P, Ganne N, Loustaud-Ratti V, D'Alteroche L, Causse X, Geist C, Minello A, Rosa I, Gelu-Simeon M, Portal I, Raffi F, Bourliere M, Pol S; French ANRS CO22 Hepather cohort. Carrat F, et al. Among authors: mathurin p. Lancet. 2019 Apr 6;393(10179):1453-1464. doi: 10.1016/S0140-6736(18)32111-1. Epub 2019 Feb 11. Lancet. 2019. PMID: 30765123
[Epidemiology of alcoholic liver disease and new challenges].
Deltenre P, Mathurin P. Deltenre P, et al. Among authors: mathurin p. Gastroenterol Clin Biol. 2009 Dec;33(12):1147-50. doi: 10.1016/j.gcb.2009.10.002. Gastroenterol Clin Biol. 2009. PMID: 19896787 French. No abstract available.
Early liver transplantation for severe alcoholic hepatitis.
Mathurin P, Moreno C, Samuel D, Dumortier J, Salleron J, Durand F, Castel H, Duhamel A, Pageaux GP, Leroy V, Dharancy S, Louvet A, Boleslawski E, Lucidi V, Gustot T, Francoz C, Letoublon C, Castaing D, Belghiti J, Donckier V, Pruvot FR, Duclos-Vallée JC. Mathurin P, et al. N Engl J Med. 2011 Nov 10;365(19):1790-800. doi: 10.1056/NEJMoa1105703. N Engl J Med. 2011. PMID: 22070476 Clinical Trial.
The cumulative 6-month survival rate (±SE) was higher among patients who received early transplantation than among those who did not (77 ± 8% vs. 23 ± 8%, P<0.001). This benefit of early transplantation was maintained through 2 years of follow-up (hazard ratio, 6.08; …
The cumulative 6-month survival rate (±SE) was higher among patients who received early transplantation than among those who did not (77 ± 8 …
A randomized trial of prednisolone in patients with severe alcoholic hepatitis.
Ramond MJ, Poynard T, Rueff B, Mathurin P, Théodore C, Chaput JC, Benhamou JP. Ramond MJ, et al. Among authors: mathurin p. N Engl J Med. 1992 Feb 20;326(8):507-12. doi: 10.1056/NEJM199202203260802. N Engl J Med. 1992. PMID: 1531090 Clinical Trial.
By the 66th day after randomization, 16 of 29 placebo recipients had died (mean [+/- SE] survival, 45 +/- 8 percent), as compared with 4 of 32 prednisolone recipients (survival, 88 +/- 5 percent) (log-rank test, 10.9; P = 0.001). ...
By the 66th day after randomization, 16 of 29 placebo recipients had died (mean [+/- SE] survival, 45 +/- 8 percent), as compared with 4 of …
Efficacy of long term recombinant interferon-alfa in patients with chronic hepatitis C. A clinical, biological, histological and immunohistological study.
Poynard T, Bedossa P, Mathurin P, Naveau S, Delfraissy JF, Lemaigre G, Chaput JC. Poynard T, et al. Among authors: mathurin p. Gastroenterol Clin Biol. 1991;15(8-9):615-9. Gastroenterol Clin Biol. 1991. PMID: 1752373
Ischemic hepatitis due to obstructive sleep apnea.
Mathurin P, Durand F, Ganne N, Mollo JL, Lebrec D, Degott C, Erlinger S, Benhamou JP, Bernuau J. Mathurin P, et al. Gastroenterology. 1995 Nov;109(5):1682-4. doi: 10.1016/0016-5085(95)90659-2. Gastroenterology. 1995. PMID: 7557154
A multidimensional case-control study of dietary, alcohol, and tobacco habits in alcoholic men with chronic pancreatitis.
Lévy P, Mathurin P, Roqueplo A, Rueff B, Bernades P. Lévy P, et al. Among authors: mathurin p. Pancreas. 1995 Apr;10(3):231-8. doi: 10.1097/00006676-199504000-00003. Pancreas. 1995. PMID: 7624300

Patients with pancreatitis consumed more nonalcohol calories than cirrhotics (p < 0.05). The percentage of calories taken as proteins (p < 0.0003) and lipids (p < 0.0001) was higher and the percentage of calories taken as alcohol (p < 0.000

Patients with pancreatitis consumed more nonalcohol calories than cirrhotics (p < 0.05). The percentage of calories taken as prote

Transforming growth factor beta 1: in situ expression in the liver of patients with chronic hepatitis C treated with alpha interferon.
Bedossa P, Poynard T, Mathurin P, Lemaigre G, Chaput JC. Bedossa P, et al. Among authors: mathurin p. Gut. 1993;34(2 Suppl):S146-7. doi: 10.1136/gut.34.2_suppl.s146. Gut. 1993. PMID: 8314486 Free PMC article.
The reduction in TGF beta 1 correlated significantly with the scores for inflammation (p < 0.05) and necrosis (p < 0.05), but not with the alanine aminotransferase activities (p = 0.36) or the score for fibrosis (p = 0.86)....

The reduction in TGF beta 1 correlated significantly with the scores for inflammation (p < 0.05) and necrosis (p < 0.05)

Meta-analysis of interferon randomized trials in the treatment of viral hepatitis C: effects of dose and duration.
Poynard T, Leroy V, Cohard M, Thevenot T, Mathurin P, Opolon P, Zarski JP. Poynard T, et al. Among authors: mathurin p. Hepatology. 1996 Oct;24(4):778-89. doi: 10.1002/hep.510240405. Hepatology. 1996. PMID: 8855176

There was a significant duration effect (12 vs. 6 months) upon the sustained response rate both at the dose of 3 MU with a mean of 16% (9% to 23%; P < .001), and at the dose of 6 MU three times per week with a mean of 20% (7% to 33%; P = .003). In acute hepatitis

There was a significant duration effect (12 vs. 6 months) upon the sustained response rate both at the dose of 3 MU with a mean of 16% (9% t …
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