Matsson P - Search Results

1

Identification of novel specific and general inhibitors of the three major human ATP-binding cassette transporters P-gp, BCRP and MRP2 among registered drugs.

Matsson P, Pedersen JM, Norinder U, Bergström CA, Artursson P. Matsson P, et al. Pharm Res. 2009 Aug;26(8):1816-31. doi: 10.1007/s11095-009-9896-0. Epub 2009 May 7. Pharm Res. 2009. PMID: 19421845

2

Exploring the role of different drug transport routes in permeability screening.

Matsson P, Bergström CA, Nagahara N, Tavelin S, Norinder U, Artursson P. Matsson P, et al. J Med Chem. 2005 Jan 27;48(2):604-13. doi: 10.1021/jm049711o. J Med Chem. 2005. PMID: 15658873

3

A global drug inhibition pattern for the human ATP-binding cassette transporter breast cancer resistance protein (ABCG2).

Matsson P, Englund G, Ahlin G, Bergström CA, Norinder U, Artursson P. Matsson P, et al. J Pharmacol Exp Ther. 2007 Oct;323(1):19-30. doi: 10.1124/jpet.107.124768. Epub 2007 Jul 6. J Pharmacol Exp Ther. 2007. PMID: 17616561

4

Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).

Pedersen JM, Matsson P, Bergström CA, Norinder U, Hoogstraate J, Artursson P. Pedersen JM, et al. Among authors: matsson p. J Med Chem. 2008 Jun 12;51(11):3275-87. doi: 10.1021/jm7015683. Epub 2008 May 6. J Med Chem. 2008. PMID: 18457386

5

Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.

Ahlin G, Karlsson J, Pedersen JM, Gustavsson L, Larsson R, Matsson P, Norinder U, Bergström CA, Artursson P. Ahlin G, et al. Among authors: matsson p. J Med Chem. 2008 Oct 9;51(19):5932-42. doi: 10.1021/jm8003152. Epub 2008 Sep 13. J Med Chem. 2008. PMID: 18788725

6

Discovery of regulatory elements in human ATP-binding cassette transporters through expression quantitative trait mapping.

Matsson P, Yee SW, Markova S, Morrissey K, Jenkins G, Xuan J, Jorgenson E, Kroetz DL, Giacomini KM. Matsson P, et al. Pharmacogenomics J. 2012 Jun;12(3):214-26. doi: 10.1038/tpj.2011.8. Epub 2011 Mar 8. Pharmacogenomics J. 2012. PMID: 21383772 Free PMC article.

7

Rapid measurement of intracellular unbound drug concentrations.

Mateus A, Matsson P, Artursson P. Mateus A, et al. Among authors: matsson p. Mol Pharm. 2013 Jun 3;10(6):2467-78. doi: 10.1021/mp4000822. Epub 2013 May 15. Mol Pharm. 2013. PMID: 23631740

8

Early identification of clinically relevant drug interactions with the human bile salt export pump (BSEP/ABCB11).

Pedersen JM, Matsson P, Bergström CA, Hoogstraate J, Norén A, LeCluyse EL, Artursson P. Pedersen JM, et al. Among authors: matsson p. Toxicol Sci. 2013 Dec;136(2):328-43. doi: 10.1093/toxsci/kft197. Epub 2013 Sep 6. Toxicol Sci. 2013. PMID: 24014644 Free PMC article.

9

Quantifying the impact of transporters on cellular drug permeability.

Matsson P, Fenu LA, Lundquist P, Wiśniewski JR, Kansy M, Artursson P. Matsson P, et al. Trends Pharmacol Sci. 2015 May;36(5):255-62. doi: 10.1016/j.tips.2015.02.009. Epub 2015 Mar 19. Trends Pharmacol Sci. 2015. PMID: 25799456 Review.

10

Computational modeling to predict the functions and impact of drug transporters.

Matsson P, Bergström CA. Matsson P, et al. In Silico Pharmacol. 2015 Dec;3(1):8. doi: 10.1186/s40203-015-0012-3. Epub 2015 Sep 4. In Silico Pharmacol. 2015. PMID: 26820893 Free PMC article.

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