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PKC- and MAPK-independent upregulation of VEGF receptor expressions in human umbilical venous endothelial cells following VEGF stimulation.
Niimi Y, Mochida S, Matsui A, Inao M, Fujiwara K. Niimi Y, et al. Among authors: matsui a. Hepatol Res. 2001 Nov;21(3):261-267. doi: 10.1016/s1386-6346(01)00091-2. Hepatol Res. 2001. PMID: 11673111
Addition of VEGF at concentrations up to 100 ng/ml increased the incorporation of 3H-thymidine into the DNA in the cells in a dose-related manner. ...Such VEGF-induced upregulation of DNA synthesis and phosporylation of MAPK in the cells were attenuated by the addition of …
Addition of VEGF at concentrations up to 100 ng/ml increased the incorporation of 3H-thymidine into the DNA in the cells in a dose-re …
Japanese herbal medicine Inchin-ko-to as a therapeutic drug for liver fibrosis.
Inao M, Mochida S, Matsui A, Eguchi Y, Yulutuz Y, Wang Y, Naiki K, Kakinuma T, Fujimori K, Nagoshi S, Fujiwara K. Inao M, et al. Among authors: matsui a. J Hepatol. 2004 Oct;41(4):584-91. doi: 10.1016/j.jhep.2004.06.033. J Hepatol. 2004. PMID: 15464238
DNA synthesis of stellate cells activated in vitro after isolation from normal rat liver was decreased by culture with TJ-135 in a dose-related manner, accompanied by decreased smooth muscle alpha actin expression and contractility. ...
DNA synthesis of stellate cells activated in vitro after isolation from normal rat liver was decreased by culture with TJ-135 in a do …
Extrahepatic manifestations in transgenic mice of osteopontin in hepatocytes-A clue to advent of pathological state in various organs of chronic hepatitis C patients.
Saitoh E, Matsui A, Inao M, Mimura S, Koh H, Ohno A, Nagoshi S, Kayano H, Yoshimoto T, Mochida S, Fujiwara K. Saitoh E, et al. Among authors: matsui a. Hepatol Res. 2005 Apr;31(4):197-202. doi: 10.1016/j.hepres.2005.01.010. Epub 2005 Apr 22. Hepatol Res. 2005. PMID: 15854888
Osteopontin is a cytokine essential for initiation of Th1 immune reaction. We established transgenic mice expressing osteopontin in hepatocyte, in which liver necrosis with lymphocyte infiltration developed gradually from 12 weeks of age with up-regulated osteopontin level …
Osteopontin is a cytokine essential for initiation of Th1 immune reaction. We established transgenic mice expressing osteopontin in h …
Plasma osteopontin levels in patients with fulminant hepatitis.
Matsui A, Mochida S, Ohno A, Nagoshi S, Hirose T, Fujiwara K. Matsui A, et al. Hepatol Res. 2004 Aug;29(4):202-206. doi: 10.1016/j.hepres.2004.03.009. Hepatol Res. 2004. PMID: 15288011
Osteopontin, an extracellular matrix, is a secretory glycoprotein as well essential for Th1 immune response, contributing to macrophage activation and infiltration. ...Immunohistochemical examination revealed that osteopontin was stained in macrophages positive for CD68, …
Osteopontin, an extracellular matrix, is a secretory glycoprotein as well essential for Th1 immune response, contributing to macropha …
Angiopoietin/tie receptors system may play a role during reconstruction and capillarization of the hepatic sinusoids after partial hepatectomy and liver necrosis in rats.
Kimura H, Mochida S, Inao M, Matsui A, Fujiwara K. Kimura H, et al. Among authors: matsui a. Hepatol Res. 2004 May;29(1):51-59. doi: 10.1016/j.hepres.2004.02.004. Hepatol Res. 2004. PMID: 15135347
Transgenic mice expressing osteopontin in hepatocytes as a model of autoimmune hepatitis.
Mochida S, Yoshimoto T, Mimura S, Inao M, Matsui A, Ohno A, Koh H, Saitoh E, Nagoshi S, Fujiwara K. Mochida S, et al. Among authors: matsui a. Biochem Biophys Res Commun. 2004 Apr 23;317(1):114-20. doi: 10.1016/j.bbrc.2004.02.180. Biochem Biophys Res Commun. 2004. PMID: 15047155
Osteopontin, a crucial factor for Th1 immune response, is expressed in stellate cells and macrophages activated in injured liver. ...The transgenic mice expressing osteopontin in hepatocytes may be useful as a model of autoimmune hepatitis....
Osteopontin, a crucial factor for Th1 immune response, is expressed in stellate cells and macrophages activated in injured liver. ... …
ERK/MAPK-dependent PI3K/Akt phosphorylation through VEGFR-1 after VEGF stimulation in activated hepatic stellate cells.
Takahashi M, Matsui A, Inao M, Mochida S, Fujiwara K. Takahashi M, et al. Among authors: matsui a. Hepatol Res. 2003 Jul;26(3):232-236. doi: 10.1016/s1386-6346(03)00112-8. Hepatol Res. 2003. PMID: 12850696
Re-evaluation of the Guideline published by the Acute Liver Failure Study Group of Japan in 1996 to determine the indications of liver transplantation in patients with fulminant hepatitis.
Mochida S, Nakayama N, Matsui A, Nagoshi S, Fujiwara K. Mochida S, et al. Among authors: matsui a. Hepatol Res. 2008 Oct;38(10):970-9. doi: 10.1111/j.1872-034X.2008.00368.x. Epub 2008 May 7. Hepatol Res. 2008. PMID: 18462374
This Guideline was prepared based on the clinical findings in patients seen between 1988 and 1992, and showed a predictive accuracy of 82% in the patients seen between 1993 and 1995. ...
This Guideline was prepared based on the clinical findings in patients seen between 1988 and 1992, and showed a predictive accuracy o …
Fulminant hepatitis and late onset hepatic failure in Japan.
Fujiwara K, Mochida S, Matsui A, Nakayama N, Nagoshi S, Toda G; Intractable Liver Diseases Study Group of Japan. Fujiwara K, et al. Among authors: matsui a. Hepatol Res. 2008 Jul;38(7):646-57. doi: 10.1111/j.1872-034X.2008.00322.x. Epub 2008 Mar 5. Hepatol Res. 2008. PMID: 18328067
AIM: A nationwide survey was performed to clarify the present state of fulminant hepatitis and late onset hepatic failure (LOHF) between 1998 and 2003 in Japan. ...
AIM: A nationwide survey was performed to clarify the present state of fulminant hepatitis and late onset hepatic failure (LOHF) betw …
Increased cytoprotective function in the liver of transgenic mice expressing osteopontin in hepatocytes.
Koh HS, Matsui A, Mimura S, Inao M, Saitoh E, Ohno A, Nagoshi S, Yoshimoto T, Mochida S, Fujiwara K. Koh HS, et al. Among authors: matsui a. Hepatol Res. 2005 May;32(1):46-51. doi: 10.1016/j.hepres.2005.01.016. Hepatol Res. 2005. PMID: 15908265
Osteopontin is a crucial factor for initiation of Th1 immune reaction. Previously, we established transgenic mice expressing osteopontin in hepatocytes, in which lymphocyte infiltration occurred spontaneously at 12 weeks of age and liver necrosis at 24 weeks of age. ...
Osteopontin is a crucial factor for initiation of Th1 immune reaction. Previously, we established transgenic mice expressing osteopon …
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