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913 results
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Modulation of TGF-beta signaling during progression of chronic liver diseases.
Matsuzaki K. Matsuzaki K. Front Biosci (Landmark Ed). 2009 Jan 1;14:2923-34. doi: 10.2741/3423. Front Biosci (Landmark Ed). 2009. PMID: 19273245 Review.
Differential regulation of TGF-beta signal in hepatic stellate cells between acute and chronic rat liver injury.
Tahashi Y, Matsuzaki K, Date M, Yoshida K, Furukawa F, Sugano Y, Matsushita M, Himeno Y, Inagaki Y, Inoue K. Tahashi Y, et al. Hepatology. 2002 Jan;35(1):49-61. doi: 10.1053/jhep.2002.30083. Hepatology. 2002. PMID: 11786959
Distortion of autocrine transforming growth factor beta signal accelerates malignant potential by enhancing cell growth as well as PAI-1 and VEGF production in human hepatocellular carcinoma cells.
Sugano Y, Matsuzaki K, Tahashi Y, Furukawa F, Mori S, Yamagata H, Yoshida K, Matsushita M, Nishizawa M, Fujisawa J, Inoue K. Sugano Y, et al. Oncogene. 2003 Apr 17;22(15):2309-21. doi: 10.1038/sj.onc.1206305. Oncogene. 2003. PMID: 12700666
p38 MAPK mediates fibrogenic signal through Smad3 phosphorylation in rat myofibroblasts.
Furukawa F, Matsuzaki K, Mori S, Tahashi Y, Yoshida K, Sugano Y, Yamagata H, Matsushita M, Seki T, Inagaki Y, Nishizawa M, Fujisawa J, Inoue K. Furukawa F, et al. Hepatology. 2003 Oct;38(4):879-89. doi: 10.1053/jhep.2003.50384. Hepatology. 2003. PMID: 14512875
TGF-beta and HGF transmit the signals through JNK-dependent Smad2/3 phosphorylation at the linker regions.
Mori S, Matsuzaki K, Yoshida K, Furukawa F, Tahashi Y, Yamagata H, Sekimoto G, Seki T, Matsui H, Nishizawa M, Fujisawa J, Okazaki K. Mori S, et al. Oncogene. 2004 Sep 23;23(44):7416-29. doi: 10.1038/sj.onc.1207981. Oncogene. 2004. PMID: 15326485
Acceleration of Smad2 and Smad3 phosphorylation via c-Jun NH(2)-terminal kinase during human colorectal carcinogenesis.
Yamagata H, Matsuzaki K, Mori S, Yoshida K, Tahashi Y, Furukawa F, Sekimoto G, Watanabe T, Uemura Y, Sakaida N, Yoshioka K, Kamiyama Y, Seki T, Okazaki K. Yamagata H, et al. Cancer Res. 2005 Jan 1;65(1):157-65. Cancer Res. 2005. PMID: 15665291
Transforming growth factor-beta and platelet-derived growth factor signal via c-Jun N-terminal kinase-dependent Smad2/3 phosphorylation in rat hepatic stellate cells after acute liver injury.
Yoshida K, Matsuzaki K, Mori S, Tahashi Y, Yamagata H, Furukawa F, Seki T, Nishizawa M, Fujisawa J, Okazaki K. Yoshida K, et al. Am J Pathol. 2005 Apr;166(4):1029-39. doi: 10.1016/s0002-9440(10)62324-3. Am J Pathol. 2005. PMID: 15793284 Free PMC article.
Reversible Smad-dependent signaling between tumor suppression and oncogenesis.
Sekimoto G, Matsuzaki K, Yoshida K, Mori S, Murata M, Seki T, Matsui H, Fujisawa J, Okazaki K. Sekimoto G, et al. Cancer Res. 2007 Jun 1;67(11):5090-6. doi: 10.1158/0008-5472.CAN-06-4629. Cancer Res. 2007. PMID: 17545585
Chronic inflammation associated with hepatitis C virus infection perturbs hepatic transforming growth factor beta signaling, promoting cirrhosis and hepatocellular carcinoma.
Matsuzaki K, Murata M, Yoshida K, Sekimoto G, Uemura Y, Sakaida N, Kaibori M, Kamiyama Y, Nishizawa M, Fujisawa J, Okazaki K, Seki T. Matsuzaki K, et al. Hepatology. 2007 Jul;46(1):48-57. doi: 10.1002/hep.21672. Hepatology. 2007. PMID: 17596875
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