Mattern MR - Search Results

1

Ubiquitin-based anticancer therapy: carpet bombing with proteasome inhibitors vs surgical strikes with E1, E2, E3, or DUB inhibitors.

Mattern MR, Wu J, Nicholson B. Mattern MR, et al. Biochim Biophys Acta. 2012 Nov;1823(11):2014-21. doi: 10.1016/j.bbamcr.2012.05.005. Epub 2012 May 17. Biochim Biophys Acta. 2012. PMID: 22610084 Free PMC article.

2

Active site-targeted covalent irreversible inhibitors of USP7 impair the functions of Foxp3+ T-regulatory cells by promoting ubiquitination of Tip60.

Wang F, Wang L, Wu J, Sokirniy I, Nguyen P, Bregnard T, Weinstock J, Mattern M, Bezsonova I, Hancock WW, Kumar S. Wang F, et al. PLoS One. 2017 Dec 13;12(12):e0189744. doi: 10.1371/journal.pone.0189744. eCollection 2017. PLoS One. 2017. PMID: 29236775 Free PMC article.

3

Discovery of Therapeutic Deubiquitylase Effector Molecules: Current Perspectives.

Nicholson B, Kumar S, Agarwal S, Eddins MJ, Marblestone JG, Wu J, Kodrasov MP, LaRocque JP, Sterner DE, Mattern MR. Nicholson B, et al. Among authors: mattern mr. J Biomol Screen. 2014 Aug;19(7):989-99. doi: 10.1177/1087057114527312. Epub 2014 Mar 14. J Biomol Screen. 2014. PMID: 24632661 Review.

4

Selective Dual Inhibitors of the Cancer-Related Deubiquitylating Proteases USP7 and USP47.

Weinstock J, Wu J, Cao P, Kingsbury WD, McDermott JL, Kodrasov MP, McKelvey DM, Suresh Kumar KG, Goldenberg SJ, Mattern MR, Nicholson B. Weinstock J, et al. Among authors: mattern mr. ACS Med Chem Lett. 2012 Sep 11;3(10):789-92. doi: 10.1021/ml200276j. eCollection 2012 Oct 11. ACS Med Chem Lett. 2012. PMID: 24900381 Free PMC article.

5

Novel approach for characterizing ubiquitin E3 ligase function.

Marblestone JG, Suresh Kumar KG, Eddins MJ, Leach CA, Sterner DE, Mattern MR, Nicholson B. Marblestone JG, et al. Among authors: mattern mr. J Biomol Screen. 2010 Dec;15(10):1220-8. doi: 10.1177/1087057110380456. Epub 2010 Sep 23. J Biomol Screen. 2010. PMID: 20864734

6

Strategies for the identification of novel inhibitors of deubiquitinating enzymes.

Goldenberg SJ, McDermott JL, Butt TR, Mattern MR, Nicholson B. Goldenberg SJ, et al. Among authors: mattern mr. Biochem Soc Trans. 2008 Oct;36(Pt 5):828-32. doi: 10.1042/BST0360828. Biochem Soc Trans. 2008. PMID: 18793145 Free PMC article. Review.

7

Analysis of ubiquitin E3 ligase activity using selective polyubiquitin binding proteins.

Marblestone JG, Larocque JP, Mattern MR, Leach CA. Marblestone JG, et al. Among authors: mattern mr. Biochim Biophys Acta. 2012 Nov;1823(11):2094-7. doi: 10.1016/j.bbamcr.2012.06.013. Epub 2012 Jun 18. Biochim Biophys Acta. 2012. PMID: 22721718 Free PMC article.

8

Comprehensive ubiquitin E2 profiling of ten ubiquitin E3 ligases.

Marblestone JG, Butt S, McKelvey DM, Sterner DE, Mattern MR, Nicholson B, Eddins MJ. Marblestone JG, et al. Among authors: mattern mr. Cell Biochem Biophys. 2013 Sep;67(1):161-7. doi: 10.1007/s12013-013-9627-3. Cell Biochem Biophys. 2013. PMID: 23695783

9

Targeting the ubiquitin E3 ligase MuRF1 to inhibit muscle atrophy.

Eddins MJ, Marblestone JG, Suresh Kumar KG, Leach CA, Sterner DE, Mattern MR, Nicholson B. Eddins MJ, et al. Among authors: mattern mr. Cell Biochem Biophys. 2011 Jun;60(1-2):113-8. doi: 10.1007/s12013-011-9175-7. Cell Biochem Biophys. 2011. PMID: 21448668

10

Characterization of selective ubiquitin and ubiquitin-like protease inhibitors using a fluorescence-based multiplex assay format.

Tian X, Isamiddinova NS, Peroutka RJ, Goldenberg SJ, Mattern MR, Nicholson B, Leach C. Tian X, et al. Among authors: mattern mr. Assay Drug Dev Technol. 2011 Apr;9(2):165-73. doi: 10.1089/adt.2010.0317. Epub 2010 Dec 6. Assay Drug Dev Technol. 2011. PMID: 21133675 Free PMC article.

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